71-831-0

Tocris Bioscience™ UNC 6934

Manufacturer: Fischer Scientific

CAS Number: 2561494-77-5

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Chemical Name or Material

N-Cyclopropyl-3,4-dihydro-3-oxo-N-[[4-[(4-pyrimidinylamino)carbonyl]phenyl]methyl]-2H-1,4-benzoxazine-7-carboxamide

Quantity

10 mg

Molecular Formula

C24H21N5O4

CAS

2561494-77-5

Target

Lysine Methyltransferase Inhibitors

Other Options

Image Product Name Manufacturer Price Range
7249487
Tocris Bioscience™ UNC 6934
Fischer Scientific --
71-835-0
Tocris Bioscience™ UNC 6934
Fischer Scientific ₹ 1,05,105.33
50-251-1050
eMolecules​ Medchem Express / UNC6934 / 5mg / 705861071 / HY-145103 / / 2561494-77-5 / [null] / 443.463 / C24H21N5O4
eMolecules​ ₹ 28,967.19
AR023P4L
N-Cyclopropyl-3-oxo-N-[4-(4-pyrimidinylcarbamoyl)benzyl]-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide
Aaron Chemicals LLC ₹ 36,876.36 - ₹ 1,17,816.12

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Description

  • UNC 6934 binds to the N-terminal proline-tryptophan-tryptophan-proline (PWWP) domain of nuclear receptor-binding SET domain-containing 2 (NSD2)
  • UNC 6934 inhibits PWWP1 interaction with nucleosomal H3K36me2 (IC50 = 104 nM) by occupying the canonical H3K36me2-binding pocket of PWWP1
  • It selectively binds endogenous NSD2 in cells and causes accumulation of endogenous NSD2 in the nucleolus.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Chemical Name or Material:
N-Cyclopropyl-3,4-dihydro-3-oxo-N-[[4-[(4-pyrimidinylamino)carbonyl]phenyl]methyl]-2H-1,4-benzoxazine-7-carboxamide

Quantity:
10 mg

Molecular Formula:
C24H21N5O4

CAS:
2561494-77-5

Target:
Lysine Methyltransferase Inhibitors

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Chemical Name or Material:
N-Cyclopropyl-3,4-dihydro-3-oxo-N-[[4-[(4-pyrimidinylamino)carbonyl]phenyl]methyl]-2H-1,4-benzoxazine-7-carboxamide

Quantity:
50 mg

Molecular Formula:
C24H21N5O4

CAS:
2561494-77-5

Target:
Lysine Methyltransferase Inhibitors

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