63-875

A 485

Manufacturer: Fischer Scientific

CAS Number: 1889279-16-6

Select a Size

Pack Size SKU Availability Price
Each of 1 63-875-Each-of-1 In Stock ₹ 30,801.60

63-875 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

CAS

1889279-16-6

Quantity

5 mg

Formula Weight

536.48

Synonym

(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide

Molecular Formula

C25H24F4N4O5

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
7139256
A 485
Fischer Scientific --
63-872-5
A 485
Fischer Scientific ₹ 1,20,126.24
50-225-9308
Medchemexpress LLC HY-107455 100mg , A-485 CAS:1889279-16-6 Purity:>98%
Medchemexpress LLC ₹ 84,447.72
50-225-9920
Medchemexpress LLC HY-107455 50mg , A-485 CAS:1889279-16-6 Purity:>98%
Medchemexpress LLC ₹ 48,961.71
NC1682625
Selleck Chemical LLC A-485 2mg 1889279-16-6
Selleck Chemical LLC ₹ 20,226.38
NC1475784
Medchemexpress LLC A-485 | 1889279-16-6 | MFCD31619258 | 5 mg
Medchemexpress LLC ₹ 20,213.55
SML2192
A-485
Sigma Aldrich ₹ 19,409.23 - ₹ 78,318.88
CS-8185
A-485
ChemScene ₹ 9,411.60 - ₹ 80,426.40
AX63058
1889279-16-6 | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide
A2B Chem ₹ 3,850.20 - ₹ 63,827.76

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Description

  • Potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor (IC50 values are 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively)
  • Displays > 1000-fold selectivity over closely related HATs
  • Suppresses proliferation in several hematological malignancies and AR+ prostate cancer cell lines in vitro
  • Inhibits tumor growth in a castration-resistant prostate cancer xenograft model
  • Orally bioavailable
  • To request the negative control for A 485, please fill out the A 486 request form on the SGC website.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Show Difference

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Fischer Scientific

63-875

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CAS:
1889279-16-6

Quantity:
5 mg

Formula Weight:
536.48

Synonym:
(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide

Molecular Formula:
C25H24F4N4O5

Purity:
98%

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CAS:
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Quantity:
100μg

Formula Weight:
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