7139256
A 485
Histone Acetyltransferase Inhibitors
Manufacturer: Fischer Scientific
CAS Number: 1889279-16-6
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CAS
1889279-16-6
Molecular Formula
C25H24F4N4O5
Purity
98%
Synonym
(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide
Formula Weight
536.48
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | A 485 | Fischer Scientific | ₹ 30,801.60 | |
| | A 485 | Fischer Scientific | ₹ 1,20,126.24 | |
 | Medchemexpress LLC HY-107455 100mg , A-485 CAS:1889279-16-6 Purity:>98% | Medchemexpress LLC | ₹ 84,447.72 | |
| | Medchemexpress LLC HY-107455 50mg , A-485 CAS:1889279-16-6 Purity:>98% | Medchemexpress LLC | ₹ 48,961.71 | |
 | Selleck Chemical LLC A-485 2mg 1889279-16-6 | Selleck Chemical LLC | ₹ 20,226.38 | |
 | Medchemexpress LLC A-485 | 1889279-16-6 | MFCD31619258 | 5 mg | Medchemexpress LLC | ₹ 20,213.55 | |
 | A-485 | Sigma Aldrich | ₹ 19,409.23 - ₹ 78,318.88 | |
 | A-485 | ChemScene | ₹ 9,411.60 - ₹ 80,426.40 | |
 | 1889279-16-6 | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide | A2B Chem | ₹ 3,850.20 - ₹ 63,827.76 |
Related Products
Description
- Potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor (IC50 values are 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively)
- Displays > 1000-fold selectivity over closely related HATs
- Suppresses proliferation in several hematological malignancies and AR+ prostate cancer cell lines in vitro
- Inhibits tumor growth in a castration-resistant prostate cancer xenograft model
- Orally bioavailable
- To request the negative control for A 485, please fill out the A 486 request form on the SGC website.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
CAS: 1889279-16-6
Molecular Formula: C25H24F4N4O5
Purity: 98%
Synonym: (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide
Formula Weight: 536.48
CAS:
1889279-16-6
Molecular Formula:
C25H24F4N4O5
Purity:
98%
Synonym:
(1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide
Formula Weight:
536.48
CAS: 1357302-64-7
Molecular Formula: C15H15NO
Purity: 98%
Synonym: 4′-((1R,2S)-2-aminocyclopropyl)biphenyl-3-ol
Formula Weight: 225.29
CAS:
1357302-64-7
Molecular Formula:
C15H15NO
Purity:
98%
Synonym:
4′-((1R,2S)-2-aminocyclopropyl)biphenyl-3-ol
Formula Weight:
225.29
CAS: 168982-69-2
Molecular Formula: C16H27NO4
Purity: __
Synonym: 3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide
Formula Weight: 297.39
CAS:
168982-69-2
Molecular Formula:
C16H27NO4
Purity:
__
Synonym:
3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide
Formula Weight:
297.39
CAS: __
Molecular Formula: C22H23ClF3N5O
Purity: 98%
Synonym: (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide
Formula Weight: 465.91
CAS:
__
Molecular Formula:
C22H23ClF3N5O
Purity:
98%
Synonym:
(3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide
Formula Weight:
465.91