77-411-0
Tocris Bioscience™ STING agonist C53
Manufacturer: Fischer Scientific
CAS Number: 2259624-71-8
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 77-411-0-Each-of-1 | In Stock | ₹ 19,090.50 |
77-411-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 19,090.50
GST (18%): ₹ 3,436.29
Total Price: ₹ 22,526.79
Chemical Name or Material
1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide
Quantity
10 mg
Molecular Formula
C25H19ClF4N2O2
CAS
2259624-71-8
Target
STING Agonists
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ STING agonist C53 | Fischer Scientific | -- | |
| | Tocris Bioscience™ STING agonist C53 | Fischer Scientific | ₹ 79,833.00 | |
 | eMolecules Medchem Express / STING agonist-12 / 5mg / 719836172 / HY-147010 / / 2259624-71-8 / [null] / 490.880 / C25H19ClF4N2O2 | eMolecules | ₹ 13,100.80 |
Related Products
Description
- STING agonist C53 is an activator of human STING (EC50 = 185 nM)
- It promotes the oligomerization and activation of human STING through a mechanism orthogonal to that of cGAMP
- STING agonist C53 increases activity of STING variants in HEK293T cells (107%, 92% and 92% reporter activity against H232, R232 and HAQ, respectively)
- It induces phosphorylation of STING variants in human tumor cell lines and PBMCs
- STING agonist C53 is active at human but not mouse STING
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide
Quantity: 10 mg
Molecular Formula: C25H19ClF4N2O2
CAS: 2259624-71-8
Target: STING Agonists
Purity: 0.98
Chemical Name or Material:
1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide
Quantity:
10 mg
Molecular Formula:
C25H19ClF4N2O2
CAS:
2259624-71-8
Target:
STING Agonists
Purity:
0.98
Chemical Name or Material: 1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide
Quantity: 50 mg
Molecular Formula: C25H19ClF4N2O2
CAS: 2259624-71-8
Target: STING Agonists
Purity: 0.98
Chemical Name or Material:
1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide
Quantity:
50 mg
Molecular Formula:
C25H19ClF4N2O2
CAS:
2259624-71-8
Target:
STING Agonists
Purity:
0.98
Chemical Name or Material: __
Quantity: 1 mg
Molecular Formula: __
CAS: 1872435-09-0
Target: __
Purity: 0.95
Chemical Name or Material:
__
Quantity:
1 mg
Molecular Formula:
__
CAS:
1872435-09-0
Target:
__
Purity:
0.95
Chemical Name or Material: 2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate
Quantity: 10 mg
Molecular Formula: C19H25NO10
CAS: 1361993-37-4
Target: Glycobiology Probes
Purity: 0.95
Chemical Name or Material:
2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate
Quantity:
10 mg
Molecular Formula:
C19H25NO10
CAS:
1361993-37-4
Target:
Glycobiology Probes
Purity:
0.95