77-415-0

Tocris Bioscience™ STING agonist C53

Manufacturer: Fischer Scientific

CAS Number: 2259624-71-8

Select a Size

Pack Size SKU Availability Price
Each of 1 77-415-0-Each-of-1 In Stock ₹ 76,747.32

77-415-0 - Each of 1

₹ 76,747.32

In Stock

Quantity

1

Base Price: ₹ 76,747.32

GST (18%): ₹ 13,814.518

Total Price: ₹ 90,561.838

Chemical Name or Material

1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide

Quantity

50 mg

Molecular Formula

C25H19ClF4N2O2

CAS

2259624-71-8

Target

STING Agonists

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250154
Tocris Bioscience™ STING agonist C53
Fischer Scientific --
77-411-0
Tocris Bioscience™ STING agonist C53
Fischer Scientific ₹ 18,352.62
50-245-4193
eMolecules​ Medchem Express / STING agonist-12 / 5mg / 719836172 / HY-147010 / / 2259624-71-8 / [null] / 490.880 / C25H19ClF4N2O2
eMolecules​ ₹ 12,594.43

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Description

  • STING agonist C53 is an activator of human STING (EC50 = 185 nM)
  • It promotes the oligomerization and activation of human STING through a mechanism orthogonal to that of cGAMP
  • STING agonist C53 increases activity of STING variants in HEK293T cells (107%, 92% and 92% reporter activity against H232, R232 and HAQ, respectively)
  • It induces phosphorylation of STING variants in human tumor cell lines and PBMCs
  • STING agonist C53 is active at human but not mouse STING
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

77-415-0

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Chemical Name or Material:
1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide

Quantity:
50 mg

Molecular Formula:
C25H19ClF4N2O2

CAS:
2259624-71-8

Target:
STING Agonists

Purity:
0.98

Img

Tocris Bioscience™

77-421

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Chemical Name or Material:
__

Quantity:
1 mg

Molecular Formula:
__

CAS:
1872435-09-0

Target:
__

Purity:
0.95

Img

Tocris Bioscience™

77-501-0

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Chemical Name or Material:
2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate

Quantity:
10 mg

Molecular Formula:
C19H25NO10

CAS:
1361993-37-4

Target:
Glycobiology Probes

Purity:
0.95

Img

Tocris Bioscience™

77-511-0

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Chemical Name or Material:
(2 S,3 R,4 R,5 S,6 R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(pent-4-ynamido)tetrahydro-2 H-pyran-2-yl hexanoate

Quantity:
10 mg

Molecular Formula:
C17H27NO7

CAS:
__

Target:
GlcNAc Detection

Purity:
0.95