A-485
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 1889279-16-6
Synonym(S): N-(4-fluorobenzyl)-2-((R)-5-(3-methylureido)-2′,4′-dioxo-2,3-dihydrospiro[indene-1,5′-ozazolidine]-3′-7 yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide, Spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide, N-[(4-fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-, (1R)-
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML2192-5-MG | In Stock | ₹ 19,409.23 |
| 25 MG | SML2192-25-MG | In Stock | ₹ 78,318.88 |
SML2192 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 19,409.23
GST (18%): ₹ 3,493.661
Total Price: ₹ 22,902.891
Quality Level
100
Assay
≥98% (HPLC)
form
powder
optical activity
[α]/D +40 to +50°, c = 0.5 in methanol
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CNC(NC1=CC=C2C(CC[C@]23C(N(CC(N(CC4=CC=C(F)C=C4)[C@@H](C)C(F)(F)F)=O)C(O3)=O)=O)=C1)=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | A 485 | Fischer Scientific | -- | |
| | A 485 | Fischer Scientific | ₹ 30,801.60 | |
| | A 485 | Fischer Scientific | ₹ 1,20,126.24 | |
 | Medchemexpress LLC HY-107455 100mg , A-485 CAS:1889279-16-6 Purity:>98% | Medchemexpress LLC | ₹ 84,447.72 | |
| | Medchemexpress LLC HY-107455 50mg , A-485 CAS:1889279-16-6 Purity:>98% | Medchemexpress LLC | ₹ 48,961.71 | |
 | Selleck Chemical LLC A-485 2mg 1889279-16-6 | Selleck Chemical LLC | ₹ 20,226.38 | |
 | Medchemexpress LLC A-485 | 1889279-16-6 | MFCD31619258 | 5 mg | Medchemexpress LLC | ₹ 20,213.55 | |
 | A-485 | ChemScene | ₹ 9,411.60 - ₹ 80,426.40 | |
 | 1889279-16-6 | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide | A2B Chem | ₹ 3,850.20 - ₹ 63,827.76 |
Related Products
Description
- Application: A-485 has been used as a p300 regulated RelA acetylation inhibitor to study the effect of fatty acid oxidation (FAO) derived cytoplasmic acetyl-CoA on CD47 transcription and protein stability via citrate/acetyl-CoA mediated RelA acetylation in glioblastoma.[1]
- Biochem/physiol Actions: A-485 exhibits an anti-tumor effect and may show therapeutic effects against the growth hormone pituitary adenoma (GHPA). It can specifically block the acetylation of histone H3 lysine 27 (H3K27) and lysine 18 (H3K18) sites catalyzed by p300.[2]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
optical activity: [α]/D +40 to +50°, c = 0.5 in methanol
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: CNC(NC1=CC=C2C(CC[C@]23C(N(CC(N(CC4=CC=C(F)C=C4)[C@@H](C)C(F)(F)F)=O)C(O3)=O)=O)=C1)=O
Quality Level: __
Assay: ≥98% (HPLC)
form: powder
optical activity: __
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: BrC1=CC2=C(NC3=CC(OC)=C(OC)C(OC)=C3)C=CN=C2C=C1
Quality Level: __
Assay: ≥98% (HPLC)
form: powder
optical activity: __
color: dark green to black
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: CN(C1=CC(OC)=C(OC)C(OC)=C1)C2=C3C(C=CC(C(F)(F)F)=C3)=NC=C2
