SML1984

GSK9311

≥98% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 1923851-49-3

Synonym(S): (R)-N-(1,3-Dimethyl-6-(2-methylpiperazin-1-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-N-ethyl-2-methoxybenzamide, N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxybenzamide

Select a Size

Pack Size SKU Availability Price
5 MG SML1984-5-MG In Stock ₹ 11,377.50

SML1984 - 5 MG

₹ 11,377.50

In Stock

Quantity

1

Base Price: ₹ 11,377.50

GST (18%): ₹ 2,047.95

Total Price: ₹ 13,425.45

Assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 90 to 100°, c = 0.3 in methanol

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

O=C1N(C)C2=CC(N3CCNC[C@H]3C)=C(N(CC)C(C4=C(OC)C=CC=C4)=O)C=C2N1C

Other Options

Image Product Name Manufacturer Price Range
50-193-1929
Medchemexpress LLC HY-100729 5mg Medchemexpress, GSK9311 CAS:1923851-49-3 Purity:>98%
Medchemexpress LLC ₹ 8,085.42
AX63588
1923851-49-3 | Gsk9311
A2B Chem ₹ 11,122.80 - ₹ 85,645.56

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Description

  • Biochem/physiol Actions: GSK9311 is a negative control for the SGC epigenetic probe GSK6853. GSK9311 exhibits 125- and 185-fold reduced potency than its structural analog GSK6853 toward BRPF1 in cell-free and cell-based assays (pIC50 = 6.0/GSK9311 vs. 8.1/GSK6853 in ligand competition binding assay by TR-FRET; IC50 = 3.7 μM/GSK9311 vs. 20 nM/GSK6853 against NanoLuc-BRPF1 bromodomain interaction with Histone H3.3-HaloTag in HEK293 cells), and therefore serves as a good inactive control compound in BRPF1 inhibition studies employing GSK6853. For characterization details of the active probe, GSK6853, please visit the GSK6853 probe summary on the Structural Genomics Consortium (SGC) website.GSK6853, the active probe, is available from Sigma. To learn more about and purchase GSK6853, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
  • Features and Benefits: GSK9311 is the negative control for GSK6853, an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Show Difference

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Sigma Aldrich

SML1984

≥98% (HPLC)...


Assay:
≥98% (HPLC)

form:
powder

optical activity:
[α]/D 90 to 100°, c = 0.3 in methanol

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear (warmed)

storage temp.:
−20°C

SMILES string:
O=C1N(C)C2=CC(N3CCNC[C@H]3C)=C(N(CC)C(C4=C(OC)C=CC=C4)=O)C=C2N1C

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Sigma Aldrich

SML1985

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≥98% (HPLC)

form:
powder

optical activity:
[α]/D -45 to -55°, c = 0.3 in methanol

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear

storage temp.:
−20°C

SMILES string:
O=C1N(C)C2=CC(N3CCNC[C@H]3C)=C(NC(C4=C(OC)C=CC=C4)=O)C=C2N1C

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Sigma Aldrich

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≥98% (HPLC)

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powder

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__

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yellow to orange

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DMSO: 2 mg/mL, clear

storage temp.:
2-8°C

SMILES string:
CN(C(/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(N(C)C=C4)C4=C3N2C5CCCCC5)=O)C

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Assay:
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storage temp.:
−20°C

SMILES string:
O=C(N1)C(C)=CC2=C1C(N[C@H]3[C@H](OCC4CCC(F)(F)CC4)CNC[C@H]3OC)=NC=C2C5=CN=CC(C)=C5