SML1862

TP-472

≥98% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2079895-62-6

Synonym(S): 3-(6-Acetyl-pyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide

Select a Size

Pack Size SKU Availability Price
5 MG SML1862-5-MG In Stock ₹ 16,383.60
25 MG SML1862-25-MG In Stock ₹ 63,336.60

SML1862 - 5 MG

₹ 16,383.60

In Stock

Quantity

1

Base Price: ₹ 16,383.60

GST (18%): ₹ 2,949.048

Total Price: ₹ 19,332.648

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C)C1=CC(C2=C(C)C=CC(C(NC3CC3)=O)=C2)=C4N=CC=CN41

Other Options

Image Product Name Manufacturer Price Range
AX65817
2079895-62-6 | 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide
A2B Chem ₹ 2,481.24 - ₹ 10,780.56

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Description

  • Biochem/physiol Actions: TP-472 is a selective probe for bromodomain-containing proteins BRD9 and BRD7. This BRD9/7 probe was developed out of a collaborative effort by Takeda and the SGC, and is of a different chemotype from BRD9/7 probes previously available. TP-472 has a KD value of 33nM for BRD9 and 340nM for BRD7 by ITC. It is >30 fold selective for BRD9 over all other bromodomain family members except BRD7. It is suitable for in vivo applications. For full characterization details, please visit the TP-472 probe summary on the Structural Genomics Consortium (SGC) website.TP-472N is used as a negative control and is available from Sigma. To learn more about and purchase TP-472N, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
  • Features and Benefits: TP-472 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC

SAFETY INFORMATION

WGK

WGK 3

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O=C(C)C1=CC(C2=C(C)C=CC(C(NC3CC3)=O)=C2)=C4N=CC=CN41

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FC(F)CN1C2=C(C=C(Cl)C=C2)C(N[C@H]3CCN(C(NC(C)C)=O)C3)=NC4=C1C=CC(F)=C4

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2-8°C

SMILES string:
OC(C(C=C1)=CC=C1COCC2=CSC3=C2C(NC(C(NCC4=CC=CC(OC)=C4)=O)=N3)=O)=O