SML1933

TP-472N

≥98% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2080306-24-5

Synonym(S): 1-[8-[2-(Cyclopropylmethoxy)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]-ethanone

Select a Size

Pack Size SKU Availability Price
5 MG SML1933-5-MG In Stock ₹ 16,383.60

SML1933 - 5 MG

₹ 16,383.60

In Stock

Quantity

1

Base Price: ₹ 16,383.60

GST (18%): ₹ 2,949.048

Total Price: ₹ 19,332.648

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C)C1=CC(C2=CC=CC=C2OCC3CC3)=C4N=CC=CN41

Other Options

Image Product Name Manufacturer Price Range
50-173-7264
Sigma Aldrich Fine Chemicals Biosciences TP-472N >=98% (HPLC) | 2080306-24-5 | MFCD30720894 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 18,551.97
BC74549
2080306-24-5 | Ethanone, 1-[8-[2-(cyclopropylmethoxy)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]-
A2B Chem --

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Description

  • Biochem/physiol Actions: TP-472N is a negative control probe for TP-472. TP-472 is a selective probe for bromodomain-containing proteins BRD9 and BRD7. The BRD9/7 probe was developed out of a collaborative effort by Takeda and the SGC, and is of a different chemotype from BRD9/7 probes previously available. TP-472 has a KD value of 33nM for BRD9 and 340nM for BRD7 by ITC, is >30 fold selective for BRD9 over all other bromodomain family members except BRD7, and is suitable for in vivo applications. The negative control TP-472N is inactive against other bromodomains (>20μM against BRD9). For full characterization details of TP-472 and TP-472N, please visit the TP-472 probe summary on the Structural Genomics Consortium (SGC) website.TP-472, the active BRD9/7 probe, is available from Sigma. To learn more about and purchase TP-472, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
  • Features and Benefits: TP-472N is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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SML1933

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Quality Level:
100

Assay:
≥98% (HPLC)

form:
powder

color:
white to beige

solubility:
DMSO: 15 mg/mL, clear

storage temp.:
2-8°C

SMILES string:
O=C(C)C1=CC(C2=CC=CC=C2OCC3CC3)=C4N=CC=CN41

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__

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2-8°C

SMILES string:
O[C@@H]1[C@@H]([C@@H](O)C2=CC=CC=C2)O[C@@H](N3C(N=CN=C4N)=C4C=C3)[C@@H]1O

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Assay:
≥98% (HPLC)

form:
powder

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear (warmed)

storage temp.:
2-8°C

SMILES string:
CN(C(/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(NC=C4)C4=C3N2C5CCCCC5)=O)C

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storage temp.:
−20°C

SMILES string:
O=C1N(C)C2=CC(N3CCNC[C@H]3C)=C(N(CC)C(C4=C(OC)C=CC=C4)=O)C=C2N1C