SML2325

BAY-6035

≥98% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2247890-13-5

Synonym(S): (2S)-1-(3-Azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-7-carboxamide, BAY 6035, BAY6035

Select a Size

Pack Size SKU Availability Price
5 MG SML2325-5-MG In Stock ₹ 11,940.00
25 MG SML2325-25-MG In Stock ₹ 38,450.00

SML2325 - 5 MG

₹ 11,940.00

In Stock

Quantity

1

Base Price: ₹ 11,940.00

GST (18%): ₹ 2,149.20

Total Price: ₹ 14,089.20

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C1C[C@H](C)N(C(N2CC(C3)C3C2)=O)C4=CC=C(C(NCCC5CC5)=O)C=C4N1

Other Options

Image Product Name Manufacturer Price Range
50-245-3781
eMolecules​ Medchem Express / BAY-6035 / 5mg / 719835650 / HY-112080 / / 2247890-13-5 / [null] / 396.491 / C22H28N4O3
eMolecules​ ₹ 12,594.43

Related Products

Img

Sigma Aldrich

SML2220

≥98% (HPLC)...

Img

Sigma Aldrich

SML2112

≥98% (HPLC)...

Img

Sigma Aldrich

SML1862

≥98% (HPLC)...

Img

Sigma Aldrich

SML2214

≥98% (HPLC)...

Img

Sigma Aldrich

SML2219

≥98% (HPLC)...

Img

Sigma Aldrich

SML1867

≥98% (HPLC)...

Img

Sigma Aldrich

SML1979

≥98% (HPLC)...

Img

Sigma Aldrich

SML1985

≥98% (HPLC)...

Description

  • Biochem/physiol Actions: BAY-6035 is a substrate-competitive, potent and selective SMYD3 inhibitor (IC50 = 88 nM by cell-free MEKK2 peptide methylation; IC50 = 70 nM against cellular MEKK2 methylation) with >100-fold selectivity over other histone methyltransferases. BAY-211 is a structural analog and the recommended inactive control (IC50 = 23 μM by cell-free MEKK2 peptide methylation) for BAY-6035. For characterization details of BAY-6035, please visit the BAY-6035 probe summary on the Structural Genomics Consortium (SGC) website.BAY-444 is the negative control for the active probe, BAY-6035. To request a sample of the negative control from the SGC, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
  • Features and Benefits: BAY-6035 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

SML2325

≥98% (HPLC)...


Assay:
≥98% (HPLC)

form:
powder

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear

storage temp.:
−20°C

SMILES string:
O=C1C[C@H](C)N(C(N2CC(C3)C3C2)=O)C4=CC=C(C(NCCC5CC5)=O)C=C4N1

Img

Sigma Aldrich

SML2340

≥98% (HPLC)...


Assay:
≥98% (HPLC)

form:
powder

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear

storage temp.:
2-8°C

SMILES string:
ClC(C=C1)=CC=C1C2=CC(CNCCCCSC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](O)[C@@H]3O)=CC=C2

Img

Sigma Aldrich

SML2342

≥98% (HPLC)...


Assay:
≥98% (HPLC)

form:
powder

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear

storage temp.:
2-8°C

SMILES string:
ClC(C=C1)=CC=C1C2=CC(CN(C(CC(C)(C)C(C(C(C)=C3C)=O)=C(C)C3=O)=O)CCCCSC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H]7[C@@H]4OC(C)(C)O7)=CC=C2

Img

Sigma Aldrich

SML2343

≥98 mg/mL (HPLC)...


Assay:
__

form:
powder

color:
white to beige

solubility:
DMSO: 2 mg/mL, clear

storage temp.:
−20°C

SMILES string:
ClC(C=C1)=CC=C1C2=CC(CN(C(CC(C)(C)C(C(C(C)=C3C)=O)=C(C)C3=O)=O)CCCCSC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H](O)[C@@H]4O)=CC=C2