67-905

Tocris™ GSK 126

Manufacturer: Tocris™

CAS Number: 1346574-57-9

Select a Size

Pack Size SKU Availability Price
Each of 1 67-905-Each-of-1 In Stock ₹ 10,027.63

67-905 - Each of 1

₹ 10,027.63

In Stock

Quantity

1

Base Price: ₹ 10,027.63

GST (18%): ₹ 1,804.973

Total Price: ₹ 11,832.603

Chemical Name or Material

N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide

Quantity

5 mg

Formula Weight

526.67

Purity

98%

CAS

1346574-57-9

Molecular Formula

C31H38N6O2

Product Type

Inhibitor

Other Options

Image Product Name Manufacturer Price Range
50-190-4802
Apexbio Technology LLC GSK126, 100mg. Cas: 1346574-57-9 MFCD: MFCD23381067. EZH2 inhibitor
Apexbio Technology LLC ₹ 34,224.00
50-149-2519
Medchemexpress LLC HY-13470 200mg , GSK126 EZH2 inhibitor;GSK2816126A CAS:1346574-57-9 Purity:98%
Medchemexpress LLC ₹ 71,151.70
50-225-9098
Medchemexpress LLC HY-13470 50mg , GSK126 CAS:1346574-57-9 Purity:>98%
Medchemexpress LLC ₹ 25,873.34
50-187-2892
Medchemexpress LLC GSK126 | 1346574-57-9 | MFCD23381067 | 5mg
Medchemexpress LLC ₹ 6,468.34
NC1463289
Cayman Chemical GSK126, 1346574-57-9, 1 mg
Cayman Chemical ₹ 6,100.43
NC0761027
Cayman Chemical GSK126, 1346574-57-9, 5 mg
Cayman Chemical ₹ 11,807.28
NC0944306
Selleck Chemical LLC GSK126 5mg 1346574-57-9 GSK2816126A, GSK2816126
Selleck Chemical LLC ₹ 15,092.78
AE35687
1346574-57-9 | Gsk126
A2B Chem ₹ 4,791.36 - ₹ 27,721.44

Related Products

Img

Tocris™

71-605

--

Img

Tocris™

69-621-0

--

Img

Tocris Bioscience™

80-045

--

Img

Tocris Bioscience™

80-052

--

Img

Tocris™

69-985

--

Img

Tocris™

62-385

--

Img

Tocris™

66-065

--

Img

R&D Systems

37-845

--

Description

  • GSK 126 is a very high affinity and selective EZH2 inhibitor (Ki = 0.5 - 3 nM)
  • Exhibits >150-fold selectivity for EZH2 over EZH1 and >1000-fold selectivity over 20 other human methyltransferases
  • Inhibits proliferation of B-cell lymphoma cell lines in vitro
  • Also inhibits H3K27Me3 and tumor growth in mice bearing BCL xenografts
  • Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection
  • Promotes the transition of ESCs to feeder-free extended pluripotent stem (EPS) cells in combination with LCDM cocktail .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Tocris™

67-905

--


Chemical Name or Material:
N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide

Quantity:
5 mg

Formula Weight:
526.67

Purity:
98%

CAS:
1346574-57-9

Molecular Formula:
C31H38N6O2

Product Type:
Inhibitor

Img

MilliporeSigma™

67-910-21MG

--


Chemical Name or Material:
__

Quantity:
1 mg

Formula Weight:
__

Purity:
__

CAS:
__

Molecular Formula:
__

Product Type:
__

Img

Fischer Scientific

67-912-5

--


Chemical Name or Material:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide

Quantity:
25 mg

Formula Weight:
3939

Purity:
98%

CAS:
695207-56-8

Molecular Formula:
C22H27N3O4S

Product Type:
__

Img

Fischer Scientific

67-915

--


Chemical Name or Material:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide

Quantity:
5 mg

Formula Weight:
1111

Purity:
98%

CAS:
695207-56-8

Molecular Formula:
C22H27N3O4S

Product Type:
__