7082170

Tocris Bioscience™ ML 179

Selective liver receptor homolog 1 (LRH1) inverse agonist

Manufacturer: Fischer Scientific

CAS Number: 1883548-87-5

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Chemical Name or Material

ML 179

Synonym

3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione

Molecular Formula

C21H25F3N4O2

Physical Form

Crystalline Solid

Purity

>99%

CAS

1883548-87-5

Solubility

Soluble to 50mM in DMSO

Formula Weight

422.44

Product Type

Bioactive Small Molecule

Other Options

Image Product Name Manufacturer Price Range
495710
Tocris Bioscience™ ML 179
Fischer Scientific ₹ 26,499.64
495750
Tocris Bioscience™ ML 179
Fischer Scientific ₹ 1,10,663.30
50-246-3728
eMolecules​ Medchem Express / ML179 / 5mg / 784544748 / HY-110329 / / 1883548-87-5 / MFCD25563255 / 422.452 / C21H25F3N4O2
eMolecules​ ₹ 18,891.65
AX65197
1883548-87-5 | 3-CYCLOHEXYL-6-[4-[3-(TRIFLUOROMETHYL)PHENYL]-1-PIPERAZINYL]-2,4(1H,3H)-PYRIMIDINEDIONE
A2B Chem ₹ 3,422.40 - ₹ 62,373.24

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Description

  • Selective liver receptor homolog 1 (LRH1, NR5A2) inverse agonist (IC50 = 320 nM and maximum efficacy of 64% repression)
  • Exhibits >31-fold selectivity over SF1.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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Selective liver receptor homolog 1 ...


Chemical Name or Material:
ML 179

Synonym:
3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione

Molecular Formula:
C21H25F3N4O2

Physical Form:
Crystalline Solid

Purity:
>99%

CAS:
1883548-87-5

Solubility:
Soluble to 50mM in DMSO

Formula Weight:
422.44

Product Type:
Bioactive Small Molecule

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(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone

Molecular Formula:
C25H25N3O2

Physical Form:
Solid

Purity:
>98%

CAS:
1415407-60-1

Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol

Formula Weight:
399.48

Product Type:
Bioactive Small Molecule

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Chemical Name or Material:
JTE 607 dihydrochloride

Synonym:
N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride

Molecular Formula:
C25H31Cl2N3O5·2HCl

Physical Form:
Solid

Purity:
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Bioactive Small Molecule

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Synonym:
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Molecular Formula:
C13H11N5O3

Physical Form:
Powder

Purity:
>98%

CAS:
1414963-82-8

Solubility:
Soluble to 100mM in 1eq. HCl and to 100mM in DMSO

Formula Weight:
285.26

Product Type:
Bioactive Small Molecule