7082179
Tocris Bioscience™ TC-I 2014
Potent TRPM8 antagonist
Manufacturer: Fischer Scientific
CAS Number: 1221349-53-6
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Chemical Name or Material
TC-I 2014
Synonym
3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Molecular Formula
C23H19F6N3O
Physical Form
Powder
Purity
>98%
CAS
1221349-53-6
Solubility
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight
467.41
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ TC-I 2014 | Fischer Scientific | ₹ 27,293.64 | |
| | Tocris Bioscience™ TC-I 2014 | Fischer Scientific | ₹ 1,13,880.36 | |
 | 1221349-53-6 | TC-I2014 | A2B Chem | ₹ 5,646.96 - ₹ 1,17,131.64 |
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Description
- Potent TRPM8 antagonist (IC50 values are 0.8, 3.0 and 4.4 nM for canine, human and rat channels respectively)
- Exhibits antiallodynic properties in pain models in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: TC-I 2014
Synonym: 3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Molecular Formula: C23H19F6N3O
Physical Form: Powder
Purity: >98%
CAS: 1221349-53-6
Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight: 467.41
Product Type: Bioactive Small Molecule
Chemical Name or Material:
TC-I 2014
Synonym:
3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Molecular Formula:
C23H19F6N3O
Physical Form:
Powder
Purity:
>98%
CAS:
1221349-53-6
Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight:
467.41
Product Type:
Bioactive Small Molecule
Chemical Name or Material: Ras GTPase Inhibitors
Synonym: 6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile
Molecular Formula: C25H20N4O3
Physical Form: Solid
Purity: >98%
CAS: 361185-42-4
Solubility: Soluble to 100mM in DMSO
Formula Weight: 424.45
Product Type: Bioactive Small Molecule
Chemical Name or Material:
Ras GTPase Inhibitors
Synonym:
6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile
Molecular Formula:
C25H20N4O3
Physical Form:
Solid
Purity:
>98%
CAS:
361185-42-4
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
424.45
Product Type:
Bioactive Small Molecule
Chemical Name or Material: PFK 15
Synonym: 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
Molecular Formula: C17H12N2O
Physical Form: Solid
Purity: >99%
CAS: 4382-63-2
Solubility: Soluble to 100mM in DMSO
Formula Weight: 260.29
Product Type: Bioactive Small Molecule
Chemical Name or Material:
PFK 15
Synonym:
1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
Molecular Formula:
C17H12N2O
Physical Form:
Solid
Purity:
>99%
CAS:
4382-63-2
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
260.29
Product Type:
Bioactive Small Molecule
Chemical Name or Material: VU 0469650 hydrochloride
Synonym: 3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
Molecular Formula: C22H28N4O·HCl
Physical Form: Solid
Purity: >98%
CAS: 1443748-47-7
Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
Formula Weight: 400.94
Product Type: Bioactive Small Molecule
Chemical Name or Material:
VU 0469650 hydrochloride
Synonym:
3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
Molecular Formula:
C22H28N4O·HCl
Physical Form:
Solid
Purity:
>98%
CAS:
1443748-47-7
Solubility:
Soluble to 100mM in DMSO and to 50mM in ethanol
Formula Weight:
400.94
Product Type:
Bioactive Small Molecule