7082188
Tocris Bioscience™ VU 0469650 Hydrochloride
Potent and selective negative allosteric modulator of mGlu1
Manufacturer: Fischer Scientific
CAS Number: 1443748-47-7
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Chemical Name or Material
VU 0469650 hydrochloride
Synonym
3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
Molecular Formula
C22H28N4O·HCl
Physical Form
Solid
Purity
>98%
CAS
1443748-47-7
Solubility
Soluble to 100mM in DMSO and to 50mM in ethanol
Formula Weight
400.94
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ VU 0469650 Hydrochloride | Fischer Scientific | ₹ 25,606.40 | |
| | Tocris Bioscience™ VU 0469650 Hydrochloride | Fischer Scientific | ₹ 1,06,792.57 | |
 | 1443748-47-7 | (R)-3-(4-(Adamantane-1-carbonyl)-3-methylpiperazin-1-yl)picolinonitrile | A2B Chem | ₹ 17,026.44 - ₹ 96,083.88 |
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Description
- Potent and selective negative allosteric modulator of mGlu1 (IC50 = 99 nM)
- Exhibits >100-fold selectivity for mGlu1 over mGlu2-8 and 68 other GPCRs, ion channels, kinases and transporters
- Brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: VU 0469650 hydrochloride
Synonym: 3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
Molecular Formula: C22H28N4O·HCl
Physical Form: Solid
Purity: >98%
CAS: 1443748-47-7
Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
Formula Weight: 400.94
Product Type: Bioactive Small Molecule
Chemical Name or Material:
VU 0469650 hydrochloride
Synonym:
3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
Molecular Formula:
C22H28N4O·HCl
Physical Form:
Solid
Purity:
>98%
CAS:
1443748-47-7
Solubility:
Soluble to 100mM in DMSO and to 50mM in ethanol
Formula Weight:
400.94
Product Type:
Bioactive Small Molecule
Chemical Name or Material: AM 6545
Synonym: 5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
Molecular Formula: C26H23Cl2N5O3S
Physical Form: Solid
Purity: >98%
CAS: 1245626-05-4
Solubility: Soluble to 20mM in DMSO
Formula Weight: 556.46
Product Type: Bioactive Small Molecule
Chemical Name or Material:
AM 6545
Synonym:
5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
Molecular Formula:
C26H23Cl2N5O3S
Physical Form:
Solid
Purity:
>98%
CAS:
1245626-05-4
Solubility:
Soluble to 20mM in DMSO
Formula Weight:
556.46
Product Type:
Bioactive Small Molecule
Chemical Name or Material: QAQ dichloride
Synonym: 2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
Molecular Formula: C28H44Cl2N6O2
Physical Form: Solid
Purity: >98%
CAS: __
Solubility: Soluble to 50mM in water
Formula Weight: 567.59
Product Type: Bioactive Small Molecule
Chemical Name or Material:
QAQ dichloride
Synonym:
2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride
Molecular Formula:
C28H44Cl2N6O2
Physical Form:
Solid
Purity:
>98%
CAS:
__
Solubility:
Soluble to 50mM in water
Formula Weight:
567.59
Product Type:
Bioactive Small Molecule
Chemical Name or Material: KRIBB11
Synonym: N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
Molecular Formula: C13H12N6O2
Physical Form: Solid
Purity: >99%
CAS: 342639-96-7
Solubility: Soluble to 100mM in DMSO
Formula Weight: 284.27
Product Type: Bioactive Small Molecule
Chemical Name or Material:
KRIBB11
Synonym:
N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine
Molecular Formula:
C13H12N6O2
Physical Form:
Solid
Purity:
>99%
CAS:
342639-96-7
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
284.27
Product Type:
Bioactive Small Molecule