7082188
Tocris Bioscience™ VU 0469650 Hydrochloride
Potent and selective negative allosteric modulator of mGlu1
Manufacturer: Fischer Scientific
CAS Number: 1443748-47-7
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Chemical Name or Material
VU 0469650 hydrochloride
Synonym
3-[(3R)-3-Methyl-4-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-1-piperazinyl]-2-pyridinecarbonitrile hydrochloride
Molecular Formula
C22H28N4O·HCl
Physical Form
Solid
Purity
>98%
CAS
1443748-47-7
Solubility
Soluble to 100mM in DMSO and to 50mM in ethanol
Formula Weight
400.94
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ VU 0469650 Hydrochloride | -- | ₹ 26,635.92 | ||
Tocris Bioscience™ VU 0469650 Hydrochloride | -- | ₹ 1,11,086.24 | ||
1443748-47-7 | (R)-3-(4-(Adamantane-1-carbonyl)-3-methylpiperazin-1-yl)picolinonitrile | -- | ₹ 17,711.00 - ₹ 99,947.00 |
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Description
- Potent and selective negative allosteric modulator of mGlu1 (IC50 = 99 nM)
- Exhibits >100-fold selectivity for mGlu1 over mGlu2-8 and 68 other GPCRs, ion channels, kinases and transporters
- Brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C