71-375-0

Tocris Bioscience™ Cambinol

Manufacturer: Fischer Scientific

CAS Number: 14513-15-6

Select a Size

Pack Size SKU Availability Price
Each of 1 71-375-0-Each-of-1 In Stock ₹ 57,667.44

71-375-0 - Each of 1

₹ 57,667.44

In Stock

Quantity

1

Base Price: ₹ 57,667.44

GST (18%): ₹ 10,380.139

Total Price: ₹ 68,047.579

Chemical Name or Material

2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone

Quantity

50 mg

Molecular Formula

C21H16N2O2S

CAS

14513-15-6

Target

SMPD2

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250145
Tocris Bioscience™ Cambinol
Fischer Scientific --
71-371-0
Tocris Bioscience™ Cambinol
Fischer Scientific ₹ 13,638.26
56-632-35MG
MilliporeSigma™ Calbiochem™ SIRT1/2 Inhibitor IV, Cambinol
MilliporeSigma™ ₹ 25,366.83
50-245-3391
eMolecules​ Medchem Express / Cambinol / 5mg / 446255965 / HY-100732 / / 14513-15-6 / MFCD09057543 / 360.430 / C21H16N2O2S
eMolecules​ ₹ 12,468.66
AA73163
14513-15-6 | Cambinol
A2B Chem ₹ 2,481.24 - ₹ 27,464.76

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Description

  • Cambinol is a neutral sphingomyelinase-2 (nSMase2) inhibitor (Ki = 7 μM; IC50 ∼ 7.7 μM)
  • In vitro , Cambinol suppresses extracellular vesicle production and inhibits cell-to-cell tau propagation in tau biosensor cells
  • In vivo , Cambinol decreases tumor necrosis factor-α or interleukin-1β-induced increases of ceramide and cell death in primary neurons
  • Cambinol is neuroprotective and brain penetrant
  • Cambinol inhibits the activity of human SIRT1 and SIRT2 and exerts antitumor activity in vitro and in mouse xenograft studies.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Show Difference

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Fischer Scientific

71-375-0

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Chemical Name or Material:
2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone

Quantity:
50 mg

Molecular Formula:
C21H16N2O2S

CAS:
14513-15-6

Target:
SMPD2

Purity:
0.98

Img

Fischer Scientific

71-400-3

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Chemical Name or Material:
__

Quantity:
11 Reactions

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

Img

Fischer Scientific

71-400-4

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Chemical Name or Material:
__

Quantity:
22 Reactions

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

Img

Fischer Scientific

71-401-3

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Chemical Name or Material:
__

Quantity:
11 Reactions

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__