7250145
Tocris Bioscience™ Cambinol
nSMase2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 14513-15-6
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Chemical Name or Material
2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone
Target
SMPD2
Purity
0.98
CAS
14513-15-6
Molecular Formula
C21H16N2O2S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Cambinol | Fischer Scientific | ₹ 13,638.26 | |
| | Tocris Bioscience™ Cambinol | Fischer Scientific | ₹ 57,667.44 | |
 | MilliporeSigma™ Calbiochem™ SIRT1/2 Inhibitor IV, Cambinol | MilliporeSigma™ | ₹ 25,366.83 | |
 | eMolecules Medchem Express / Cambinol / 5mg / 446255965 / HY-100732 / / 14513-15-6 / MFCD09057543 / 360.430 / C21H16N2O2S | eMolecules | ₹ 12,468.66 | |
 | 14513-15-6 | Cambinol | A2B Chem | ₹ 2,481.24 - ₹ 27,464.76 |
Related Products
Description
- Cambinol is a neutral sphingomyelinase-2 (nSMase2) inhibitor (Ki = 7 μM; IC50 ∼ 7.7 μM)
- In vitro , Cambinol suppresses extracellular vesicle production and inhibits cell-to-cell tau propagation in tau biosensor cells
- In vivo , Cambinol decreases tumor necrosis factor-α or interleukin-1β-induced increases of ceramide and cell death in primary neurons
- Cambinol is neuroprotective and brain penetrant
- Cambinol inhibits the activity of human SIRT1 and SIRT2 and exerts antitumor activity in vitro and in mouse xenograft studies.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone
Target: SMPD2
Purity: 0.98
CAS: 14513-15-6
Molecular Formula: C21H16N2O2S
Chemical Name or Material:
2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone
Target:
SMPD2
Purity:
0.98
CAS:
14513-15-6
Molecular Formula:
C21H16N2O2S
Chemical Name or Material: 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1 R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Target: Bcl-2 Family Inhibitors
Purity: 0.98
CAS: 923564-51-6
Molecular Formula: C47H55ClF3N5O6S3
Chemical Name or Material:
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1 R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Target:
Bcl-2 Family Inhibitors
Purity:
0.98
CAS:
923564-51-6
Molecular Formula:
C47H55ClF3N5O6S3
Chemical Name or Material: 2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine
Target: DNA, RNA and Protein Synthesis Compounds
Purity: 0.98
CAS: 101862-47-9
Molecular Formula: C10H8ClN5O
Chemical Name or Material:
2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine
Target:
DNA, RNA and Protein Synthesis Compounds
Purity:
0.98
CAS:
101862-47-9
Molecular Formula:
C10H8ClN5O
Chemical Name or Material: 6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target: LMTK3
Purity: 0.98
CAS: __
Molecular Formula: C18H11F3N4O
Chemical Name or Material:
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target:
LMTK3
Purity:
0.98
CAS:
__
Molecular Formula:
C18H11F3N4O