7110839

Tocris Bioscience™ AMG PERK 44

Potent and selective PERK inhibitor; orally bioavailable

Manufacturer: Fischer Scientific

CAS Number: 1883548-84-2

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Chemical Name or Material

4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride

Target

PERK Inhibitors

Formula Weight

561.07

CAS

1883548-84-2

Molecular Formula

C34H28N4O2.HCl

Purity

>98%

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Description

  • Potent and selective PERK inhibitor (IC50 = 6 nM)
  • Exhibits >160-fold selectivity for PERK over B-Raf and GCN2, as well as a panel of 387 other kinases
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C