7110845
Tocris Bioscience™ Sephin 1
Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
Manufacturer: Fischer Scientific
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Chemical Name or Material
(2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Molecular Formula
C8H9ClN4.CH2O3
Purity
>98%
Target
Protein Ser/Thr Phosphatase Inhibitors
Formula Weight
258.66
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Description
- Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
- Does not bind PPP1R15B or have α2 adrenergic agonist activity
- Cytoprotective in endoplasmic reticulum stressed cells in vitro
- Prevents defects associated with protein misfolding in a mouse Charcot-Marie Tooth-1B model
- Orally available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: (2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Molecular Formula: C8H9ClN4.CH2O3
Purity: >98%
Target: Protein Ser/Thr Phosphatase Inhibitors
Formula Weight: 258.66
Chemical Name or Material:
(2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Molecular Formula:
C8H9ClN4.CH2O3
Purity:
>98%
Target:
Protein Ser/Thr Phosphatase Inhibitors
Formula Weight:
258.66
Chemical Name or Material: 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride
Molecular Formula: C14H17BrN2O2.HCl
Purity: >98%
Target: Nicotinic (a7) Receptor Agonists
Formula Weight: 361.66
Chemical Name or Material:
4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride
Molecular Formula:
C14H17BrN2O2.HCl
Purity:
>98%
Target:
Nicotinic (a7) Receptor Agonists
Formula Weight:
361.66
Chemical Name or Material: 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
Molecular Formula: C14H6F2N4O
Purity: >98%
Target: Group I mGluR Antagonists
Formula Weight: 284.22
Chemical Name or Material:
3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
Molecular Formula:
C14H6F2N4O
Purity:
>98%
Target:
Group I mGluR Antagonists
Formula Weight:
284.22
Chemical Name or Material: (2R)-2-(Acetylamino)-3-mercaptopropanamide
Molecular Formula: C5H10N2O2S
Purity: __
Target: Additional Antioxidant Compounds
Formula Weight: 162.21
Chemical Name or Material:
(2R)-2-(Acetylamino)-3-mercaptopropanamide
Molecular Formula:
C5H10N2O2S
Purity:
__
Target:
Additional Antioxidant Compounds
Formula Weight:
162.21