7110898
Tocris Bioscience™ Tariquidar dihydrochloride
Potent P-glycoprotein (P-gp) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1992047-62-7
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Chemical Name or Material
N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Target
Multidrug Transporter Inhibitors
Formula Weight
719.66
CAS
1992047-62-7
Molecular Formula
C38H38N4O6.2HCl
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Tariquidar dihydrochloride | Fischer Scientific | ₹ 27,165.30 | |
| | Tocris Bioscience™ Tariquidar dihydrochloride | Fischer Scientific | ₹ 1,13,367.00 | |
 | 1992047-62-7 | N-(2-((4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide hydrochloride | A2B Chem | ₹ 16,170.84 |
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Description
- Potent P-glycoprotein (P-gp) inhibitor (IC50 = 5.1 nM)
- Reverses drug resistance in multiple MDR cell lines
- Acts as a substrate for breast cancer resistance protein (BCRP) at low concentrations and acts as an inhibitor of BCRP when used at >100 nM concentration
- Potentiates the cytotoxic effects of doxorubicin (Cat
- No
- 2252) and mitoxantrone (Cat
- No
- 4250) in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Target: Multidrug Transporter Inhibitors
Formula Weight: 719.66
CAS: 1992047-62-7
Molecular Formula: C38H38N4O6.2HCl
Purity: >98%
Chemical Name or Material:
N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Target:
Multidrug Transporter Inhibitors
Formula Weight:
719.66
CAS:
1992047-62-7
Molecular Formula:
C38H38N4O6.2HCl
Purity:
>98%
Chemical Name or Material: 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
Target: Dehydrogenase Inhibitors
Formula Weight: 412.59
CAS: 459147-39-8
Molecular Formula: C21H20N2OS3
Purity: >98%
Chemical Name or Material:
2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
Target:
Dehydrogenase Inhibitors
Formula Weight:
412.59
CAS:
459147-39-8
Molecular Formula:
C21H20N2OS3
Purity:
>98%
Chemical Name or Material: (-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Target: 5-HT Transporter Inhibitors
Formula Weight: 414.43
CAS: 219861-53-7
Molecular Formula: C20H21FN2O.C2H2O4
Purity: >98%
Chemical Name or Material:
(-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Target:
5-HT Transporter Inhibitors
Formula Weight:
414.43
CAS:
219861-53-7
Molecular Formula:
C20H21FN2O.C2H2O4
Purity:
>98%
Chemical Name or Material: 1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylic acid
Target: Sphingosine-1-phosphate Receptor Agonists
Formula Weight: 366.24
CAS: 1240308-45-5
Molecular Formula: C18H17Cl2NO3
Purity: >99%
Chemical Name or Material:
1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylic acid
Target:
Sphingosine-1-phosphate Receptor Agonists
Formula Weight:
366.24
CAS:
1240308-45-5
Molecular Formula:
C18H17Cl2NO3
Purity:
>99%