7110898
Tocris Bioscience™ Tariquidar dihydrochloride
Potent P-glycoprotein (P-gp) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1992047-62-7
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Chemical Name or Material
N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Target
Multidrug Transporter Inhibitors
Formula Weight
719.66
CAS
1992047-62-7
Molecular Formula
C38H38N4O6.2HCl
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Tariquidar dihydrochloride | -- | ₹ 28,257.50 | ||
Tocris Bioscience™ Tariquidar dihydrochloride | -- | ₹ 1,17,925.00 | ||
1992047-62-7 | N-(2-((4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide hydrochloride | -- | ₹ 16,821.00 |
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Description
- Potent P-glycoprotein (P-gp) inhibitor (IC50 = 5.1 nM)
- Reverses drug resistance in multiple MDR cell lines
- Acts as a substrate for breast cancer resistance protein (BCRP) at low concentrations and acts as an inhibitor of BCRP when used at >100 nM concentration
- Potentiates the cytotoxic effects of doxorubicin (Cat
- No
- 2252) and mitoxantrone (Cat
- No
- 4250) in vitro .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C