7110905
Tocris Bioscience™ DEL 22379
ERK dimerization inhibitor
Manufacturer: Fischer Scientific
CAS Number: 181223-80-3
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Chemical Name or Material
N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide
Target
ERK Inhibitors
Formula Weight
444.53
CAS
181223-80-3
Molecular Formula
C26H28N4O3
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ DEL 22379 | Fischer Scientific | ₹ 24,514.65 | |
| | Tocris Bioscience™ DEL 22379 | Fischer Scientific | ₹ 92,500.63 | |
 | Sigma Aldrich Fine Chemicals Biosciences DEL-22379 >=98% (HPLC) | 181223-80-3 | MFCD00950163 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,634.45 | |
| | eMolecules Medchem Express / DEL-22379 / 5mg / 446269500 / HY-18932 / / 181223-80-3 / [null] / 444.535 / C26H28N4O3 | eMolecules | ₹ 9,445.82 | |
 | Medchemexpress LLC HY-18932 5mg Medchemexpress, DEL-22379 CAS:181223-80-3 Purity:>98% | Medchemexpress LLC | ₹ 6,737.85 | |
| | Sigma Aldrich Fine Chemicals Biosciences DEL-22379 >=98% (HPLC) | 181223-80-3 | MFCD00950163 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 35,635.74 |
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Description
- ERK dimerization inhibitor (IC50 ∽ 0.5 μM); inhibits ERK dimerization without affecting phosphorylation or kinase activity
- Suppresses growth of tumor cells expressing RAS-ERK oncogenes in vitro
- Induces apoptosis and prevents tumor progression in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide
Target: ERK Inhibitors
Formula Weight: 444.53
CAS: 181223-80-3
Molecular Formula: C26H28N4O3
Purity: >98%
Chemical Name or Material:
N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide
Target:
ERK Inhibitors
Formula Weight:
444.53
CAS:
181223-80-3
Molecular Formula:
C26H28N4O3
Purity:
>98%
Chemical Name or Material: rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
Target: Tankyrase Inhibitors
Formula Weight: 428.53
CAS: 1645286-75-4
Molecular Formula: C25H28N6O
Purity: >98%
Chemical Name or Material:
rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
Target:
Tankyrase Inhibitors
Formula Weight:
428.53
CAS:
1645286-75-4
Molecular Formula:
C25H28N6O
Purity:
>98%
Chemical Name or Material: N-5-Isoquinolinyl-N′-[[(4-(trifluoromethyl)phenyl]methyl]urea
Target: TRPV Antagonists
Formula Weight: 345.32
CAS: 581809-67-8
Molecular Formula: C18H14F3N3O
Purity: >98%
Chemical Name or Material:
N-5-Isoquinolinyl-N′-[[(4-(trifluoromethyl)phenyl]methyl]urea
Target:
TRPV Antagonists
Formula Weight:
345.32
CAS:
581809-67-8
Molecular Formula:
C18H14F3N3O
Purity:
>98%
Chemical Name or Material: 1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one
Target: Additional Lipid Metabolism Compounds
Formula Weight: 405.49
CAS: 1301214-47-0
Molecular Formula: C23H27N5O2
Purity: >98%
Chemical Name or Material:
1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one
Target:
Additional Lipid Metabolism Compounds
Formula Weight:
405.49
CAS:
1301214-47-0
Molecular Formula:
C23H27N5O2
Purity:
>98%