7112874
Tocris Bioscience™ TFB-TBOA
High affinity EAAT1 and EAAT2 blocker
Manufacturer: Fischer Scientific
CAS Number: 480439-73-4
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Chemical Name or Material
(3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
Assay Percent Range
>98%
Molecular Formula
C19H17F3N2O6
CAS
480439-73-4
Solubility
Soluble to 100mM in DMSO
Formula Weight
Observed MW: 426.35
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ TFB-TBOA | Fischer Scientific | ₹ 20,336.50 | |
 | Tocris Bioscience™ TFB-TBOA | Fischer Scientific | ₹ 42,764.50 | |
 | 480439-73-4 | (3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID | A2B Chem | ₹ 22,072.00 - ₹ 84,194.00 |
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Description
- Potent and selective glial glutamate transporter EAAT1 and EAAT2 inhibitor (IC50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively)
- Has no effect on EAAT4 and EAAT5, or a wide range of neuronal receptors and transporters
- Attenuates glutamate-stimulated intracellular Na+ elevation in astrocytes in vitro (IC50 = 43 nM)
- Induces severe convulsions in vivo.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
Assay Percent Range: >98%
Molecular Formula: C19H17F3N2O6
CAS: 480439-73-4
Solubility: Soluble to 100mM in DMSO
Formula Weight: Observed MW: 426.35
Chemical Name or Material:
(3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
Assay Percent Range:
>98%
Molecular Formula:
C19H17F3N2O6
CAS:
480439-73-4
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
Observed MW: 426.35
Chemical Name or Material: N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea
Assay Percent Range: >97%
Molecular Formula: C24H18F3N3O4
CAS: 228559-41-9
Solubility: Soluble to 100mM in DMSO
Formula Weight: Observed MW: 469.41
Chemical Name or Material:
N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea
Assay Percent Range:
>97%
Molecular Formula:
C24H18F3N3O4
CAS:
228559-41-9
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
Observed MW: 469.41
Chemical Name or Material: (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide
Assay Percent Range: >99%
Molecular Formula: C11H14BrNO2.HBr
CAS: 912342-28-0
Solubility: Soluble to 100mM in DMSO
Formula Weight: Observed MW: 353.05
Chemical Name or Material:
(4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide
Assay Percent Range:
>99%
Molecular Formula:
C11H14BrNO2.HBr
CAS:
912342-28-0
Solubility:
Soluble to 100mM in DMSO
Formula Weight:
Observed MW: 353.05
Chemical Name or Material: 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid
Assay Percent Range: >98%
Molecular Formula: C24H16BrFN2O4
CAS: 853929-59-6
Solubility: Soluble to 10mM in DMSO
Formula Weight: Observed MW: 495.3
Chemical Name or Material:
2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid
Assay Percent Range:
>98%
Molecular Formula:
C24H16BrFN2O4
CAS:
853929-59-6
Solubility:
Soluble to 10mM in DMSO
Formula Weight:
Observed MW: 495.3