7114673

Tocris Bioscience™ PF 04991532

Potent hepatoselective glucokinase activator

Manufacturer: Fischer Scientific

CAS Number: 1215197-37-7

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Chemical Name or Material

6-[[(2 S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1 H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid

Assay Percent Range

>98%

Molecular Formula

C18H19F3N4O3

Purity

98%

CAS

1215197-37-7

Target

Glucokinase/GCK

Formula Weight

Observed MW: 396.36

Other Options

Image Product Name Manufacturer Price Range
634525
Tocris Bioscience™ PF 04991532
Fischer Scientific --
63455
Tocris Bioscience™ PF 04991532
Fischer Scientific --
50-245-8080
eMolecules​ Medchem Express / PF-04991532 / 5mg / 415685517 / HY-100181 / / 1215197-37-7 / MFCD27938256 / 396.370 / C18H19F3N4O3
eMolecules​ ₹ 15,113.32
50-186-2473
Sigma Aldrich Fine Chemicals Biosciences PF-04991532 >=98% (HPLC) | 1215197-37-7 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 36,893.47
CS-0018176
PF-04991532
ChemScene ₹ 10,267.20 - ₹ 78,715.20
AE63591
1215197-37-7 | (S)-6-(3-Cyclopentyl-2-(4-(trifluoroMethyl)-1H-iMidazol- 1-yl)propanaMido)nicotinic Acid
A2B Chem ₹ 13,860.72 - ₹ 75,891.72

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Description

  • Potent hepatoselective glucokinase activator (EC50 = 90 nM)
  • Exhibits >50-fold liver to pancreas ratio of tissue distribution
  • Reduces fasting and postprandial glucose levels with no hypoglycemia in a rat diabetes model.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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Fischer Scientific

7114673

Potent hepatoselective glucokinase ...


Chemical Name or Material:
6-[[(2 S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1 H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid

Assay Percent Range:
>98%

Molecular Formula:
C18H19F3N4O3

Purity:
98%

CAS:
1215197-37-7

Target:
Glucokinase/GCK

Formula Weight:
Observed MW: 396.36

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Assay Percent Range:
>99%

Molecular Formula:
C23H14F2NO2Na

Purity:
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96201-88-6

Target:
DHODH Inhibitors

Formula Weight:
Observed MW: 397.35

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Chemical Name or Material:
(Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate

Assay Percent Range:
>99%

Molecular Formula:
C21H20N4O3

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__

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209783-80-2

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945714-67-0

Target:
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Formula Weight:
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