7116041
AS 1949490
SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1203680-76-5
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Chemical Name or Material
3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide
Assay Percent Range
>99%
Formula Weight
Observed MW: 371.88
CAS
1203680-76-5
Molecular Formula
C20H18ClNO2S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | AS 1949490 | Fischer Scientific | ₹ 44,833.44 | |
| | AS 1949490 | Fischer Scientific | ₹ 12,029.74 | |
 | 1203680-76-5 | 3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide | A2B Chem | ₹ 2,481.24 - ₹ 22,160.04 |
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Description
- Selective SHIP2 (SH2 domain-containing inositol 5'-phosphatase 2) inhibitor (IC50 values are 0.34 μM and 0.62 μM for mouse and human respectively); displays approximately 30-fold affinity for SHIP2 over SHIP1
- Increases insulin-induced phosphorylation of Akt in L6 myotubules
- Stimulates activation of glucose metabolism; regulates gluconeogenesis in vitro and in vivo and exhibits antidiabetic effects
- Also promotes increased BDNF mRNA levels in cultured cortical neurons and has memory enhancing and antidepressant effects in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature
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Chemical Name or Material: 3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide
Assay Percent Range: >99%
Formula Weight: Observed MW: 371.88
CAS: 1203680-76-5
Molecular Formula: C20H18ClNO2S
Chemical Name or Material:
3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 371.88
CAS:
1203680-76-5
Molecular Formula:
C20H18ClNO2S
Chemical Name or Material: 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid
Assay Percent Range: >98%
Formula Weight: Observed MW: 587.07
CAS: 146362-70-1
Molecular Formula: C32H31ClN4O5
Chemical Name or Material:
2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 587.07
CAS:
146362-70-1
Molecular Formula:
C32H31ClN4O5
Chemical Name or Material: 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
Assay Percent Range: __
Formula Weight: Observed MW: 353.31
CAS: 946387-07-1
Molecular Formula: C14H22Cl2N2O2S
Chemical Name or Material:
2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
Assay Percent Range:
__
Formula Weight:
Observed MW: 353.31
CAS:
946387-07-1
Molecular Formula:
C14H22Cl2N2O2S
Chemical Name or Material: 1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
Assay Percent Range: >99%
Formula Weight: Observed MW: 441.56
CAS: 115256-11-6
Molecular Formula: C19H27N3O5S2
Chemical Name or Material:
1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 441.56
CAS:
115256-11-6
Molecular Formula:
C19H27N3O5S2