7114677
Tocris Bioscience™ FPS ZM1
High affinity antagonist of RAGE
Manufacturer: Fischer Scientific
CAS Number: 945714-67-0
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Chemical Name or Material
4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range
>99%
Formula Weight
Observed MW: 327.85
CAS
945714-67-0
Molecular Formula
C20H22ClNO
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ FPS ZM1 | Fischer Scientific | ₹ 9,282.70 | |
| | Tocris Bioscience™ FPS ZM1 | Fischer Scientific | ₹ 38,403.50 | |
 | 945714-67-0 | N-Benzyl-4-chloro-N-cyclohexylbenzamide | A2B Chem | ₹ 979.00 - ₹ 82,058.00 |
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Description
- High affinity antagonist of the receptor for advanced glycation end products (RAGE) (Ki = 25 nM)
- Blocks Aβ binding to the V domain of RAGE and inhibits Aβ40- and Aβ42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo
- Blocks β-secretase activity, Aβ production, microglia activation and neuroinflammation in vivo
- BBB permeable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range: >99%
Formula Weight: Observed MW: 327.85
CAS: 945714-67-0
Molecular Formula: C20H22ClNO
Chemical Name or Material:
4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 327.85
CAS:
945714-67-0
Molecular Formula:
C20H22ClNO
Chemical Name or Material: 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Assay Percent Range: >98%
Formula Weight: Observed MW: 638.82
CAS: 193275-84-2
Molecular Formula: C27H31Br2ClN4O2
Chemical Name or Material:
4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 638.82
CAS:
193275-84-2
Molecular Formula:
C27H31Br2ClN4O2
Chemical Name or Material: 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6 H-pyrrolo[4,3,2,ef][2 ]benzazepin-6-one (1 S,4 R)-7,7-dimethyl-2-oxobicyclo[2.2.1 ]heptane-1-methanesulfonic acid
Assay Percent Range: >98%
Formula Weight: Observed MW: 555.66
CAS: 1859053-21-6
Molecular Formula: C19H18FN3O.C10H16O4S
Chemical Name or Material:
8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6 H-pyrrolo[4,3,2,ef][2 ]benzazepin-6-one (1 S,4 R)-7,7-dimethyl-2-oxobicyclo[2.2.1 ]heptane-1-methanesulfonic acid
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 555.66
CAS:
1859053-21-6
Molecular Formula:
C19H18FN3O.C10H16O4S
Chemical Name or Material: (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide
Assay Percent Range: >98%
Formula Weight: Observed MW: 469.94
CAS: 1110813-31-4
Molecular Formula: C24H25ClFN5O2
Chemical Name or Material:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 469.94
CAS:
1110813-31-4
Molecular Formula:
C24H25ClFN5O2