7114677

Tocris Bioscience™ FPS ZM1

High affinity antagonist of RAGE

Manufacturer: Fischer Scientific

CAS Number: 945714-67-0

The price for this product is unavailable. Please request a quote

Chemical Name or Material

4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide

Assay Percent Range

>99%

Formula Weight

Observed MW: 327.85

CAS

945714-67-0

Molecular Formula

C20H22ClNO

Other Options

Image Product Name Manufacturer Price Range
62-371-0
Tocris Bioscience™ FPS ZM1
Fischer Scientific ₹ 8,923.91
62-375-0
Tocris Bioscience™ FPS ZM1
Fischer Scientific ₹ 36,919.14
AV46715
945714-67-0 | N-Benzyl-4-chloro-N-cyclohexylbenzamide
A2B Chem ₹ 941.16 - ₹ 78,886.32

Related Products

Img

Fischer Scientific

7116041

SH2 domain-containing inositol 5'-p...

Img

Fischer Scientific

7116044

Selective TRPV4 antagonist...

Img

Fischer Scientific

7116031

Highly potent and selective covalen...

Img

Fischer Scientific

7114676

HDAC (Class I) inhibitor...

Img

Fischer Scientific

7116135

Pan-histone demethylase inhibitor...

Img

Fischer Scientific

7116067

Inhibits canonical Wnt signaling. P...

Img

Fischer Scientific

7116035

KCa2.2 and KCa2.3 (SK) channel acti...

Img

Fischer Scientific

7114682

Selective, high affinity negative m...

Description

  • High affinity antagonist of the receptor for advanced glycation end products (RAGE) (Ki = 25 nM)
  • Blocks Aβ binding to the V domain of RAGE and inhibits Aβ40- and Aβ42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo
  • Blocks β-secretase activity, Aβ production, microglia activation and neuroinflammation in vivo
  • BBB permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

7114677

High affinity antagonist of RAGE...


Chemical Name or Material:
4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide

Assay Percent Range:
>99%

Formula Weight:
Observed MW: 327.85

CAS:
945714-67-0

Molecular Formula:
C20H22ClNO

Img

Fischer Scientific

7114679

Potent farnesyl transferase inhibit...


Chemical Name or Material:
4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 638.82

CAS:
193275-84-2

Molecular Formula:
C27H31Br2ClN4O2

Img

Fischer Scientific

7114680

PARP inhibitor...


Chemical Name or Material:
8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6 H-pyrrolo[4,3,2,ef][2 ]benzazepin-6-one (1 S,4 R)-7,7-dimethyl-2-oxobicyclo[2.2.1 ]heptane-1-methanesulfonic acid

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 555.66

CAS:
1859053-21-6

Molecular Formula:
C19H18FN3O.C10H16O4S

Img

Fischer Scientific

7114681

Potent irreversible pan ErbB inhibi...


Chemical Name or Material:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 469.94

CAS:
1110813-31-4

Molecular Formula:
C24H25ClFN5O2