7114676
Tocris Bioscience™ MS 275
HDAC (Class I) inhibitor
Manufacturer: Fischer Scientific
CAS Number: 209783-80-2
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Chemical Name or Material
(Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
Assay Percent Range
>99%
Formula Weight
Observed MW: 376.41
CAS
209783-80-2
Molecular Formula
C21H20N4O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ MS 275 | Fischer Scientific | ₹ 18,010.38 | |
| | Tocris Bioscience™ MS 275 | Fischer Scientific | ₹ 74,651.10 | |
 | Selleck Chemical LLC Entinostat (MS-275) 10mM/1mL 209783-80-2 SNDX-275 | Selleck Chemical LLC | ₹ 20,226.38 | |
| | Selleck Chemical LLC Entinostat (MS-275) 200mg 209783-80-2 SNDX-275 | Selleck Chemical LLC | ₹ 96,272.11 | |
 | Apexbio Technology LLC Entinostat inhibits HDAC1 and HDAC3 but not HDAC8 209783-80-2. MFCD08272435 | Apexbio Technology LLC | ₹ 8,556.00 | |
| | Selleck Chemical LLC Entinostat (MS-275) 50mg 209783-80-2 SNDX-275 | Selleck Chemical LLC | ₹ 50,177.52 | |
| | Selleck Chemical LLC Entinostat (MS-275) 10mg 209783-80-2 SNDX-275 | Selleck Chemical LLC | ₹ 15,092.78 | |
 | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate | Aaron Chemicals LLC | ₹ 1,454.52 - ₹ 12,748.44 | |
 | 209783-80-2 | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate | A2B Chem | ₹ 1,625.64 - ₹ 87,014.52 |
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Description
- Class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively)
- Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo
- Increases estrogen receptor α- and aromatase expression in breast cancer cells
- Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
Assay Percent Range: >99%
Formula Weight: Observed MW: 376.41
CAS: 209783-80-2
Molecular Formula: C21H20N4O3
Chemical Name or Material:
(Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 376.41
CAS:
209783-80-2
Molecular Formula:
C21H20N4O3
Chemical Name or Material: 4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range: >99%
Formula Weight: Observed MW: 327.85
CAS: 945714-67-0
Molecular Formula: C20H22ClNO
Chemical Name or Material:
4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 327.85
CAS:
945714-67-0
Molecular Formula:
C20H22ClNO
Chemical Name or Material: 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Assay Percent Range: >98%
Formula Weight: Observed MW: 638.82
CAS: 193275-84-2
Molecular Formula: C27H31Br2ClN4O2
Chemical Name or Material:
4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 638.82
CAS:
193275-84-2
Molecular Formula:
C27H31Br2ClN4O2
Chemical Name or Material: 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6 H-pyrrolo[4,3,2,ef][2 ]benzazepin-6-one (1 S,4 R)-7,7-dimethyl-2-oxobicyclo[2.2.1 ]heptane-1-methanesulfonic acid
Assay Percent Range: >98%
Formula Weight: Observed MW: 555.66
CAS: 1859053-21-6
Molecular Formula: C19H18FN3O.C10H16O4S
Chemical Name or Material:
8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6 H-pyrrolo[4,3,2,ef][2 ]benzazepin-6-one (1 S,4 R)-7,7-dimethyl-2-oxobicyclo[2.2.1 ]heptane-1-methanesulfonic acid
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 555.66
CAS:
1859053-21-6
Molecular Formula:
C19H18FN3O.C10H16O4S