7116120
AZD 1208
Potent pan Pim kinase inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1204144-28-4
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Chemical Name or Material
(5Z)-5-[[2-[(3R)-3-Amino-1-piperidinyl][1,1'-biphenyl]-3-yl]methylene]-2,4-thiazolidinedione
Assay Percent Range
>98%
Formula Weight
Observed MW: 379.48
CAS
1204144-28-4
Molecular Formula
C21H21N3O2S
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | AZD 1208 | Fischer Scientific | ₹ 11,975.84 | |
| | AZD 1208 | Fischer Scientific | ₹ 49,451.96 | |
 | eMolecules Ambeed / (RZ)-5-((2-(3-Aminopiperidin-1-yl)-[11-biphenyl]-3-yl)methylene)thiazolidine-24-dione / 1mg / 491169030 / A178546 / / 1204144-28-4 / MFCD25976757 / 379.480 / C21H21N3O2S | eMolecules | ₹ 2,422.58 |
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Description
- Potent pan Pim kinase inhibitor (IC50 values are 0.4, 1.9 and 5.0 nM for Pim-1, 3 and 2, respectively)
- Exhibits >43-fold higher affinity for Pim kinases over a range of other kinases
- Induces cell cycle arrest and apoptosis in AML cell lines in vitro and inhibits growth of tumor xenografts in vivo
- Chemosensitizer.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: (5Z)-5-[[2-[(3R)-3-Amino-1-piperidinyl][1,1'-biphenyl]-3-yl]methylene]-2,4-thiazolidinedione
Assay Percent Range: >98%
Formula Weight: Observed MW: 379.48
CAS: 1204144-28-4
Molecular Formula: C21H21N3O2S
Chemical Name or Material:
(5Z)-5-[[2-[(3R)-3-Amino-1-piperidinyl][1,1'-biphenyl]-3-yl]methylene]-2,4-thiazolidinedione
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 379.48
CAS:
1204144-28-4
Molecular Formula:
C21H21N3O2S
Chemical Name or Material: 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine dihydrochloride
Assay Percent Range: >99%
Formula Weight: Observed MW: 415.74
CAS: 2250025-93-3
Molecular Formula: C18H19ClN4O0.2 HCl
Chemical Name or Material:
8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine dihydrochloride
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 415.74
CAS:
2250025-93-3
Molecular Formula:
C18H19ClN4O0.2 HCl
Chemical Name or Material: (3 R,5 S,6 E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt
Assay Percent Range: >99%
Formula Weight: Observed MW: 500.57
CAS: 147098-20-2
Molecular Formula: C22H27FN3O6S.1⁄2Ca
Chemical Name or Material:
(3 R,5 S,6 E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt
Assay Percent Range:
>99%
Formula Weight:
Observed MW: 500.57
CAS:
147098-20-2
Molecular Formula:
C22H27FN3O6S.1⁄2Ca
Chemical Name or Material: 4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-pyrimidinamine
Assay Percent Range: >98%
Formula Weight: Observed MW: 419.46
CAS: 1293395-67-1
Molecular Formula: C22H22FN7O
Chemical Name or Material:
4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-pyrimidinamine
Assay Percent Range:
>98%
Formula Weight:
Observed MW: 419.46
CAS:
1293395-67-1
Molecular Formula:
C22H22FN7O