7116079

GSK 2194069

Potent human fatty acid synthase (hFASN) inhibitor

Manufacturer: Fischer Scientific

CAS Number: 1332331-08-4

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Chemical Name or Material

4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

Assay Percent Range

>99%

Formula Weight

Observed MW: 428.48

CAS

1332331-08-4

Molecular Formula

C25H24N4O3

Other Options

Image Product Name Manufacturer Price Range
53-032-5
GSK 2194069
Fischer Scientific ₹ 71,357.04
53-035
GSK 2194069
Fischer Scientific ₹ 18,951.54
50-173-7508
Sigma Aldrich Fine Chemicals Biosciences GSK2194069 >=97% (HPLC) | 1332331-08-4 | MFCD28167807 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 83,797.46
50-173-7509
Sigma Aldrich Fine Chemicals Biosciences GSK2194069 >=97% (HPLC) | 1332331-08-4 | MFCD28167807 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 21,696.30
AA52208
1332331-08-4 | 3H-1,2,4-Triazol-3-one, 4-[4-(5-benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-
A2B Chem ₹ 3,764.64 - ₹ 2,11,504.32

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Description

  • Potent human fatty acid synthase (hFASN) inhibitor (IC50 = 7.7 nM); inhibits hFAS β-ketoacyl reductase activity
  • Inhibits lipid synthesis and attenuates proliferation of A549 non-small-cell lung cancer cells (EC50 = 15 nM) in vitro .

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

Compare Similar Items

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Fischer Scientific

7116079

Potent human fatty acid synthase (h...


Chemical Name or Material:
4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

Assay Percent Range:
>99%

Formula Weight:
Observed MW: 428.48

CAS:
1332331-08-4

Molecular Formula:
C25H24N4O3

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7116081

Potent and selective cell-permeable...


Chemical Name or Material:
5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 400.35

CAS:
675103-36-3

Molecular Formula:
C20H15F3N4O2

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Inhibits Mcl-1-BIM interaction...


Chemical Name or Material:
7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol

Assay Percent Range:
>99%

Formula Weight:
Observed MW: 415.45

CAS:
315698-17-0

Molecular Formula:
C23H24F3N3O

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ULK inhibitor...


Chemical Name or Material:
N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 507.5

CAS:
__

Molecular Formula:
C25H34N6O.2HCl