7116073

CID 16020046

Selective GPR55 antagonist

Manufacturer: Fischer Scientific

CAS Number: 834903-43-4

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Chemical Name or Material

4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid

Assay Percent Range

>99%

Formula Weight

Observed MW: 425.44

CAS

834903-43-4

Molecular Formula

C25H19N3O4

Other Options

Image Product Name Manufacturer Price Range
49-592-5
CID 16020046
Fischer Scientific ₹ 60,747.60
49-595
CID 16020046
Fischer Scientific ₹ 16,222.18

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Description

  • Selective GPR55 antagonist
  • Inhibits LPI-induced Ca2+ signaling (IC50 = 0.21 μM in HEK-GPR55 cells), ERK1/2 phosphorylation and GPR55-mediated transcription factor activation
  • Displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG
  • Decreases LPI-induced GPR55 internalization
  • Reduces experimental intestinal inflammation in mice.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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Fischer Scientific

7116073

Selective GPR55 antagonist...


Chemical Name or Material:
4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid

Assay Percent Range:
>99%

Formula Weight:
Observed MW: 425.44

CAS:
834903-43-4

Molecular Formula:
C25H19N3O4

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Assay Percent Range:
>98%

Formula Weight:
Observed MW: 474.96

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355025-24-0

Molecular Formula:
C23H23ClN2O5S

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Chemical Name or Material:
4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 461.53

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Molecular Formula:
C25H23N3O4S

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Chemical Name or Material:
4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

Assay Percent Range:
>99%

Formula Weight:
Observed MW: 428.48

CAS:
1332331-08-4

Molecular Formula:
C25H24N4O3