59-561-0
Tocris Bioscience™ NF 1819
Manufacturer: Tocris Bioscience™
CAS Number: 1881244-28-5
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Chemical Name or Material
(3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone
Assay Percent Range
>98%
Molecular Formula
C24H22FN5O4
CAS
1881244-28-5
Quantity
10 mg
Formula Weight
Observed MW: 463.46
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 1881244-28-5 | (3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone | A2B Chem | ₹ 13,775.16 - ₹ 1,10,800.20 |
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Description
- NF 1819 is a potent and selective irreversible MAGL inhibitor (IC50 values are 0.25 and 7.4 nM at rMAGL and hMAGL, respectively)
- Exhibits 389-fold selectivity over hFAAH and exhibits minimal binding at CB receptors (IC50 > 10 μM)
- Alleviates symptoms in a MS in vivo model
- Exhibits analgesic effects in an acute inflammatory pain model in vivo
- Ameliorates neuropathic hypersensitivity induced by oxaliplatin (Cat
- No
- 2623)
- Displays high membrane permeability and brain penetrant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Show Difference
Chemical Name or Material: (3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone
Assay Percent Range: >98%
Molecular Formula: C24H22FN5O4
CAS: 1881244-28-5
Quantity: 10 mg
Formula Weight: Observed MW: 463.46
Chemical Name or Material:
(3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone
Assay Percent Range:
>98%
Molecular Formula:
C24H22FN5O4
CAS:
1881244-28-5
Quantity:
10 mg
Formula Weight:
Observed MW: 463.46
Chemical Name or Material: __
Assay Percent Range: __
Molecular Formula: __
CAS: __
Quantity: 250 mg
Formula Weight: __
Chemical Name or Material:
__
Assay Percent Range:
__
Molecular Formula:
__
CAS:
__
Quantity:
250 mg
Formula Weight:
__
Chemical Name or Material: (E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Assay Percent Range: __
Molecular Formula: C19H21NO4S
CAS: 143621-35-6
Quantity: 10 mg
Formula Weight: 359.44
Chemical Name or Material:
(E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Assay Percent Range:
__
Molecular Formula:
C19H21NO4S
CAS:
143621-35-6
Quantity:
10 mg
Formula Weight:
359.44
Chemical Name or Material: (E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Assay Percent Range: __
Molecular Formula: C19H21NO4S
CAS: 143621-35-6
Quantity: 50 mg
Formula Weight: 359.44
Chemical Name or Material:
(E)-4-Methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one
Assay Percent Range:
__
Molecular Formula:
C19H21NO4S
CAS:
143621-35-6
Quantity:
50 mg
Formula Weight:
359.44