7116116

Givinostat hydrochloride

Histone deacetylase inhibitor

Manufacturer: Fischer Scientific

CAS Number: 199657-29-9

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Chemical Name or Material

[6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride

Assay Percent Range

>98%

Formula Weight

Observed MW: 457.95

CAS

199657-29-9

Molecular Formula

C24H27N3O4.HCl

Other Options

Image Product Name Manufacturer Price Range
62-492-5
Givinostat hydrochloride
Fischer Scientific ₹ 47,828.04
62-495
Givinostat hydrochloride
Fischer Scientific ₹ 12,431.87
AB08980
199657-29-9 | Givinostat hydrochloride
A2B Chem ₹ 10,695.00 - ₹ 79,143.00

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Description

  • Histone deacetylase (HDAC) inhibitor (IC50 = 7.5 to 16 nM)
  • At low concentrations reduces release of pro-inflammatory cytokines, including TNFα, INFγ, IL-1α and IL-1β, from LPS stimulated PBMCs in vitro
  • Exhibits anti-inflammatory effects in vivo
  • Improves functional recovery and attenuates tissue damage in a mouse model of traumatic brain injury.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

7116116

Histone deacetylase inhibitor...


Chemical Name or Material:
[6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 457.95

CAS:
199657-29-9

Molecular Formula:
C24H27N3O4.HCl

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Fischer Scientific

7116117

High affinity and selective PCAF br...


Chemical Name or Material:
(1S, 2S)-N1,N1-Dimethyl-N2-(3-methyl-1,2,4-triazolo[3,4-a]phthalazin-6-yl)-1-phenylpropane-1,2-diamine dihydrochloride

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 433.38

CAS:
__

Molecular Formula:
C21H24N6.2HCl

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7116118

Ferroptosis activator...


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N2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 517.66

CAS:
1083162-61-1

Molecular Formula:
C25H31N3O5S2

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GPR171 antagonist...


Chemical Name or Material:
N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 237.34

CAS:
65373-29-7

Molecular Formula:
C10H11N3S2