7116057

Banoxantrone dihydrochloride

Prodrug topoisomerase II inhibitor

Manufacturer: Fischer Scientific

CAS Number: 252979-56-9

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Chemical Name or Material

1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride

Assay Percent Range

>98%

Formula Weight

Observed MW: 517.4

CAS

252979-56-9

Molecular Formula

C22H28N4O6.2HCl

Other Options

Image Product Name Manufacturer Price Range
42-192-5
Banoxantrone dihydrochloride
Fischer Scientific ₹ 41,496.60
42-195
Banoxantrone dihydrochloride
Fischer Scientific ₹ 11,131.36
50-173-9353
Sigma Aldrich Fine Chemicals Biosciences Banoxantrone dihydrochloride >=98% (HPLC) | 252979-56-9 | MFCD19690955 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 44,867.66
50-245-5795
eMolecules​ Medchem Express / Banoxantrone (dihydrochloride) / 5mg / 446263121 / HY-13562A / / 252979-56-9 / MFCD19690955 / 517.400 / C22H30Cl2N4O6
eMolecules​ ₹ 12,090.48
AX37696
252979-56-9 | BanoxantroneDihydrochloride
A2B Chem ₹ 8,128.20 - ₹ 59,892.00

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Description

  • Bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4
  • Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM)
  • Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat
  • No
  • 4091) in a mouse tumor model.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C

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Fischer Scientific

7116057

Prodrug topoisomerase II inhibitor...


Chemical Name or Material:
1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride

Assay Percent Range:
>98%

Formula Weight:
Observed MW: 517.4

CAS:
252979-56-9

Molecular Formula:
C22H28N4O6.2HCl

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Formula Weight:
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Molecular Formula:
C17H9Cl2N3O2