7116044
RN 1734
Selective TRPV4 antagonist
Manufacturer: Fischer Scientific
CAS Number: 946387-07-1
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Chemical Name or Material
2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
CAS
946387-07-1
Molecular Formula
C14H22Cl2N2O2S
Formula Weight
Observed MW: 353.31
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | RN 1734 | Fischer Scientific | ₹ 38,715.90 | |
| | RN 1734 | Fischer Scientific | ₹ 10,523.88 | |
| | MilliporeSigma™ Calbiochem™ TRPV4 Antagonist I, RN-1734 | MilliporeSigma™ | ₹ 10,369.87 | |
 | Medchemexpress LLC HY-19975 5mg Medchemexpress, RN-1734 CAS:946387-07-1 Purity:>98% | Medchemexpress LLC | ₹ 4,671.58 | |
 | 946387-07-1 | RN-1734 | A2B Chem | ₹ 1,368.96 - ₹ 17,197.56 |
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Description
- Selective TRPV4 antagonist (IC50 values are 2.3, 3.2 and 5.9 μM for hTRPV4, rTRPV4 and mTRPV4 receptors respectively)
- Displays selectivity for TRPV4 over other TRP channels (IC50 values are 2.3, >30, >30 and >100 μM for TRPV4, TRPV3, TRPM8 and TRPV1 respectively)
- Blocks TRPV4-mediated arteriole vasodilation and increases myogenic tone ex vivo.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
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Chemical Name or Material: 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
CAS: 946387-07-1
Molecular Formula: C14H22Cl2N2O2S
Formula Weight: Observed MW: 353.31
Chemical Name or Material:
2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
CAS:
946387-07-1
Molecular Formula:
C14H22Cl2N2O2S
Formula Weight:
Observed MW: 353.31
Chemical Name or Material: 1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
CAS: 115256-11-6
Molecular Formula: C19H27N3O5S2
Formula Weight: Observed MW: 441.56
Chemical Name or Material:
1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
CAS:
115256-11-6
Molecular Formula:
C19H27N3O5S2
Formula Weight:
Observed MW: 441.56
Chemical Name or Material: 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
CAS: 459168-41-3
Molecular Formula: C14H16ClN3O
Formula Weight: Observed MW: 277.75
Chemical Name or Material:
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
CAS:
459168-41-3
Molecular Formula:
C14H16ClN3O
Formula Weight:
Observed MW: 277.75
Chemical Name or Material: 2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole
CAS: 1255517-76-0
Molecular Formula: C19H21F3N6
Formula Weight: Observed MW: 390.41
Chemical Name or Material:
2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole
CAS:
1255517-76-0
Molecular Formula:
C19H21F3N6
Formula Weight:
Observed MW: 390.41