7121038
Tocris Bioscience™ Perifosine
PKB/Akt inhibitor; also modulates Kv2.1 current
Manufacturer: Fischer Scientific
CAS Number: 157716-52-4
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Chemical Name or Material
Perifosine
Synonym
Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Molecular Formula
C25H52NO4P
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
157716-52-4
Solubility
Soluble to 100mM in water and to 100mM in ethanol
Formula Weight
461.66
Color
White
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Perifosine | Fischer Scientific | ₹ 13,030.79 | |
| | Tocris Bioscience™ Perifosine | Fischer Scientific | ₹ 54,245.04 | |
 | Medchemexpress LLC HY-50909 50mg , Perifosine CAS:157716-52-4 Purity:>98% | Medchemexpress LLC | ₹ 32,611.19 | |
 | Sigma Aldrich Fine Chemicals Biosciences Perifosine >=98% (HPLC) | 157716-52-4 | 10MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 14,463.92 |
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Description
- PKB/Akt inhibitor; accumulates in and reorganizes lipid rafts disrupting Akt signaling
- Also inhibits MAPK pathway and induces autophagy
- Induces apoptosis in leukemia cell lines
- Decreases Kv2.1 current amplitude by modulating its inactivation gating
- Antitumor
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: Perifosine
Synonym: Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Molecular Formula: C25H52NO4P
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 157716-52-4
Solubility: Soluble to 100mM in water and to 100mM in ethanol
Formula Weight: 461.66
Color: White
Purity: >98%
Chemical Name or Material:
Perifosine
Synonym:
Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Molecular Formula:
C25H52NO4P
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
157716-52-4
Solubility:
Soluble to 100mM in water and to 100mM in ethanol
Formula Weight:
461.66
Color:
White
Purity:
>98%
Chemical Name or Material: Galeterone
Synonym: (3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol
Molecular Formula: C26H32N2O
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 851983-85-2
Solubility: Soluble to 50mM in DMSO and to 50mM in ethanol
Formula Weight: 388.55
Color: White
Purity: >98%
Chemical Name or Material:
Galeterone
Synonym:
(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol
Molecular Formula:
C26H32N2O
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
851983-85-2
Solubility:
Soluble to 50mM in DMSO and to 50mM in ethanol
Formula Weight:
388.55
Color:
White
Purity:
>98%
Chemical Name or Material: Ras GTPase Inhibitors
Synonym: [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Molecular Formula: C5H10N2O7P2
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 118072-93-8
Solubility: Soluble to 50mM in 1.1eq. NaOH and to 3mM in water
Formula Weight: 272.09
Color: Off-white
Purity: >98%
Chemical Name or Material:
Ras GTPase Inhibitors
Synonym:
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Molecular Formula:
C5H10N2O7P2
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
118072-93-8
Solubility:
Soluble to 50mM in 1.1eq. NaOH and to 3mM in water
Formula Weight:
272.09
Color:
Off-white
Purity:
>98%
Chemical Name or Material: PF 06409577
Synonym: 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula: C19H16ClNO3
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1467057-23-3
Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight: 341.79
Color: Gray
Purity: 99%
Chemical Name or Material:
PF 06409577
Synonym:
6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula:
C19H16ClNO3
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1467057-23-3
Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight:
341.79
Color:
Gray
Purity:
99%