7121039

Tocris Bioscience™ Galeterone

CYP17 inhibitor; also androgen receptor antagonist

Manufacturer: Fischer Scientific

CAS Number: 851983-85-2

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Chemical Name or Material

Galeterone

Synonym

(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol

Molecular Formula

C26H32N2O

Physical Form

Solid

Product Type

Bioactive Small Molecule

CAS

851983-85-2

Solubility

Soluble to 50mM in DMSO and to 50mM in ethanol

Formula Weight

388.55

Color

White

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
61-085-0
Tocris Bioscience™ Galeterone
Fischer Scientific ₹ 81,624.24
61-081-0
Tocris Bioscience™ Galeterone
Fischer Scientific ₹ 20,192.16
50-174-0419
Sigma Aldrich Fine Chemicals Biosciences Galeterone >=98% (HPLC) | 851983-85-2 | MFCD16660907 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 9,904.43
50-174-0418
Sigma Aldrich Fine Chemicals Biosciences Galeterone >=98% (HPLC) | 851983-85-2 | MFCD16660907 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 37,941.58

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Description

  • CYP17 inhibitor (IC50 = 300 nM) and androgen receptor antagonist (IC50 = 384 nM in PC3-AR cells)
  • Inhibits DHT-stimulated prostate cancer cell proliferation in vitro
  • Exhibits antitumor activity in SCID mice bearing prostate cancer xenografts.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

7121039

CYP17 inhibitor; also androgen rece...


Chemical Name or Material:
Galeterone

Synonym:
(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol

Molecular Formula:
C26H32N2O

Physical Form:
Solid

Product Type:
Bioactive Small Molecule

CAS:
851983-85-2

Solubility:
Soluble to 50mM in DMSO and to 50mM in ethanol

Formula Weight:
388.55

Color:
White

Purity:
>98%

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Chemical Name or Material:
Ras GTPase Inhibitors

Synonym:
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Molecular Formula:
C5H10N2O7P2

Physical Form:
Solid

Product Type:
Bioactive Small Molecule

CAS:
118072-93-8

Solubility:
Soluble to 50mM in 1.1eq. NaOH and to 3mM in water

Formula Weight:
272.09

Color:
Off-white

Purity:
>98%

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Chemical Name or Material:
PF 06409577

Synonym:
6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid

Molecular Formula:
C19H16ClNO3

Physical Form:
Solid

Product Type:
Bioactive Small Molecule

CAS:
1467057-23-3

Solubility:
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Formula Weight:
341.79

Color:
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Purity:
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