7121040
Tocris Bioscience™ Zoledronic Acid
Potent farnesyl diphosphate (FPP) synthase inhibitor
Manufacturer: Fischer Scientific
CAS Number: 118072-93-8
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Chemical Name or Material
Ras GTPase Inhibitors
Synonym
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Molecular Formula
C5H10N2O7P2
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
118072-93-8
Solubility
Soluble to 50mM in 1.1eq. NaOH and to 3mM in water
Formula Weight
272.09
Color
Off-white
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Zoledronic Acid | Fischer Scientific | ₹ 8,923.91 | |
| | Tocris Bioscience™ Zoledronic Acid | Fischer Scientific | ₹ 36,491.34 | |
 | Selleck Chemical LLC Zoledronic Acid 100mg 118072-93-8 Zoledronate, CGP-4244 | Selleck Chemical LLC | ₹ 27,721.44 | |
 | Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis- | Aaron Chemicals LLC | ₹ 855.60 - ₹ 33,282.84 | |
 | 118072-93-8 | Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis- | A2B Chem | ₹ 4,021.32 - ₹ 16,170.84 |
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Description
- Potent bisphophonate farnesyl diphosphate (FPP) synthase inhibitor (IC50 = 20 nM)
- Inhibits osteoclast-mediated bone resorption
- Also inhibits Ras signaling and tumor growth, and induces apoptosis in pancreatic cancer cells
- Reverses epithelial-mesenchymal transition and inhibits breast cancer cell renewal via inactivation of NF-κB.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
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Chemical Name or Material: Ras GTPase Inhibitors
Synonym: [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Molecular Formula: C5H10N2O7P2
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 118072-93-8
Solubility: Soluble to 50mM in 1.1eq. NaOH and to 3mM in water
Formula Weight: 272.09
Color: Off-white
Purity: >98%
Chemical Name or Material:
Ras GTPase Inhibitors
Synonym:
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Molecular Formula:
C5H10N2O7P2
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
118072-93-8
Solubility:
Soluble to 50mM in 1.1eq. NaOH and to 3mM in water
Formula Weight:
272.09
Color:
Off-white
Purity:
>98%
Chemical Name or Material: PF 06409577
Synonym: 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula: C19H16ClNO3
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1467057-23-3
Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight: 341.79
Color: Gray
Purity: 99%
Chemical Name or Material:
PF 06409577
Synonym:
6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Molecular Formula:
C19H16ClNO3
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1467057-23-3
Solubility:
Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight:
341.79
Color:
Gray
Purity:
99%
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