7166828
Tocris™ Idasanutlin
Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
Manufacturer: Fischer Scientific
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Molecular Formula
C31H29Cl2F2N3O4
Formula Weight
616.49
Product Type
Inhibitor
Purity
98%
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Description
- Idasanutlin is a potent MDM2 inhibitor (IC50 = 6 nM in binding assay, and 30 nM in cancer cell proliferation assay)
- Induces p53 stabilisation, cell cycle arrest and apoptosis in cancer cells expression wildtype p53
- Displays inhibition of tumor growth in the SJSA1 tumor xenograft model
- Also inhibits MDR-1 at high concentrations.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Molecular Formula: C31H29Cl2F2N3O4
Formula Weight: 616.49
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C31H29Cl2F2N3O4
Formula Weight:
616.49
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C20H23N3O
Formula Weight: 321.42
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C20H23N3O
Formula Weight:
321.42
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C15H13NO
Formula Weight: 223.28
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C15H13NO
Formula Weight:
223.28
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C22H19N5O
Formula Weight: 369.43
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C22H19N5O
Formula Weight:
369.43
Product Type:
Inhibitor
Purity:
98%