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7166831

Tocris™ CM 10

ALDH1A inhibitor; depletes CD133+ cancer stem cells (CSC)

Manufacturer: Fischer Scientific

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Molecular Formula

C20H23N3O

Formula Weight

321.42

Product Type

Inhibitor

Purity

98%

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Description

  • CM 10 is a aldehyde dehydrogenase 1A (ALDH1A) inhibitor (IC50 values are 0.64, 0.74 and 1.7 μM for ALDH1A3, ALDH1A2 and ALDH1A1, respectively)
  • Induces a necroptotic phenotype and preferentially depletes CD133+ ovarian cancer stem cells in vitro .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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