7166832
Tocris™ 673 A
ALDH1A inhibitor; depletes CD133+ cancer stem cells (CSC)
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Molecular Formula
C15H13NO
Formula Weight
223.28
Product Type
Inhibitor
Purity
98%
Related Products
Description
- 673 A is an aldehyde dehydrogenase (ALDH1A) inhibitor (IC50 values are 230, 246 and 348 nM for ALDH1A2, ALDH1A1 and ALDH1A3, respectively)
- Exhibits >40-fold selectivity for ALD1A over ALDH2
- Depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines
- Triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP)
- Overcomes chemotherapy resistance in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Molecular Formula: C15H13NO
Formula Weight: 223.28
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C15H13NO
Formula Weight:
223.28
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C22H19N5O
Formula Weight: 369.43
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C22H19N5O
Formula Weight:
369.43
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C45H50ClN7O7S
Formula Weight: 868.45
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C45H50ClN7O7S
Formula Weight:
868.45
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C21H25ClN6O2
Formula Weight: 428.92
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C21H25ClN6O2
Formula Weight:
428.92
Product Type:
Inhibitor
Purity:
98%