7166814
Tocris™ PND 1186
Potent FAK inhibitor; orally bioavailable
Manufacturer: Fischer Scientific
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Molecular Formula
C25H26F3N5O3
Formula Weight
501.51
Product Type
Inhibitor
Purity
98%
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Description
- PND 1186 is a potent FAK inhibitor (IC50 values are 1.5 and 100 nM for recombinant FAK and FAK in breast carcinoma cells, respectively)
- Promotes caspase activation; triggering apoptosis
- Inhibits 4T1 breast carcinoma subcutaneous tumor growth and breast carcinoma cell motility
- Decreases spontaneous breast to lung metastasis in pre-clinical models
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Molecular Formula: C25H26F3N5O3
Formula Weight: 501.51
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C25H26F3N5O3
Formula Weight:
501.51
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C19H14N2O7S
Formula Weight: 414.39
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C19H14N2O7S
Formula Weight:
414.39
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C20H12F5N3O4
Formula Weight: 453.33
Product Type: Antagonist
Purity: 98%
Molecular Formula:
C20H12F5N3O4
Formula Weight:
453.33
Product Type:
Antagonist
Purity:
98%
Molecular Formula: C20H31BrN2O2
Formula Weight: 411.38
Product Type: Blocker
Purity: 98%
Molecular Formula:
C20H31BrN2O2
Formula Weight:
411.38
Product Type:
Blocker
Purity:
98%