7182930
Tocris Bioscience™ OptoBI-1
Photoswitchable TRPC3/6/7 agonist
Manufacturer: Fischer Scientific
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Chemical Name or Material
1-[1-[4-[4-[(4-Butylphenyl)diazenyl]phenyl]butanoyl]piperidin-4-yl]-1,3-dihydro-2H-benzo[d]imidazol-2-one
Molecular Formula
C32H37N5O2
Purity
98%
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Description
- Description OptoBI-1 is a photoswitchable TRPC3/6/7 agonist (EC50 for active cis -form ∽0.1 μM at TRPC3)
- Switches conformation from trans to cis at 365 nm and cis to trans at 430 nm
- Returns to trans conformation in the dark after ∽ 50 minutes
- No effect observed on TRPC4 or 5
- Rapidly changes TRPC3 conductance and inhibits neuronal firing in cis -state.
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Chemical Name or Material: 1-[1-[4-[4-[(4-Butylphenyl)diazenyl]phenyl]butanoyl]piperidin-4-yl]-1,3-dihydro-2H-benzo[d]imidazol-2-one
Molecular Formula: C32H37N5O2
Purity: 98%
Chemical Name or Material:
1-[1-[4-[4-[(4-Butylphenyl)diazenyl]phenyl]butanoyl]piperidin-4-yl]-1,3-dihydro-2H-benzo[d]imidazol-2-one
Molecular Formula:
C32H37N5O2
Purity:
98%
Chemical Name or Material: 3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride
Molecular Formula: C32H34F3N5O4.2HCl
Purity: 98%
Chemical Name or Material:
3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride
Molecular Formula:
C32H34F3N5O4.2HCl
Purity:
98%
Chemical Name or Material: 5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Molecular Formula: C19H19FN2O2
Purity: 98%
Chemical Name or Material:
5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Molecular Formula:
C19H19FN2O2
Purity:
98%
Chemical Name or Material: 5-Amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide
Molecular Formula: C17H17FN4O2S
Purity: 98%
Chemical Name or Material:
5-Amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide
Molecular Formula:
C17H17FN4O2S
Purity:
98%