72-895
Tocris Bioscience™ Nimbolide
Manufacturer: Fischer Scientific
CAS Number: 25990-37-8
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-895-Each-of-1 | In Stock | ₹ 30,887.16 |
72-895 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,887.16
GST (18%): ₹ 5,559.689
Total Price: ₹ 36,446.849
Chemical Name or Material
(2 aR,5 aR,6 S,6 aR,8 R,9 aR,10 AS,10 bR,10 cR)-8-(3-Furanyl)-2 A,5 A,6,6 A,8,9,9 A,10 A,10 b,10 c-decahydro-2 A,5 A,6 A,7-tetramethyl-2,5-dioxo-2 H,5 H-cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid methyl ester
Quantity
5 mg
Molecular Formula
C27H30O7
CAS
25990-37-8
Target
Ubiquitin Ligase (E3) Inhibitors
Purity
0.97
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Nimbolide | Fischer Scientific | -- | |
| | Tocris Bioscience™ Nimbolide | Fischer Scientific | ₹ 1,28,938.92 | |
 | eMolecules Medchem Express / Nimbolide / 5mg / 599423733 / HY-116035 / / 25990-37-8 / [null] / 466.530 / C27H30O7 | eMolecules | ₹ 35,264.41 | |
 | Medchemexpress LLC HY-116035 5mg , Nimbolide CAS:25990-37-8 Purity:>98% | Medchemexpress LLC | ₹ 25,154.64 | |
| | Nimbolide | Sigma Aldrich | ₹ 1,69,627.75 | |
 | Nimbolide | Sigma Aldrich | ₹ 38,807.63 | |
 | 25990-37-8 | Nimbolide | A2B Chem | ₹ 19,336.56 - ₹ 81,538.68 |
Related Products
Description
- Nimbolide inhibits auto-ubiquitination of the E3 ligase RNF114 and p21 ubiquitination in vitro
- This compound impairs proliferation of triple-negative breast cancer cell lines
- Nimbolide also induces apoptotic cell death in a Waldenströms macroglobulinemia cell line (BCWM1) and inhibits tumor growth in a xenograft model of Waldenströms macroglobulinemia
- Nimbolide can be used for the development of Degraders that utilize RNF114 as an E3 ligase for Targeted Protein Degradation.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: (2 aR,5 aR,6 S,6 aR,8 R,9 aR,10 AS,10 bR,10 cR)-8-(3-Furanyl)-2 A,5 A,6,6 A,8,9,9 A,10 A,10 b,10 c-decahydro-2 A,5 A,6 A,7-tetramethyl-2,5-dioxo-2 H,5 H-cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid methyl ester
Quantity: 5 mg
Molecular Formula: C27H30O7
CAS: 25990-37-8
Target: Ubiquitin Ligase (E3) Inhibitors
Purity: 0.97
Chemical Name or Material:
(2 aR,5 aR,6 S,6 aR,8 R,9 aR,10 AS,10 bR,10 cR)-8-(3-Furanyl)-2 A,5 A,6,6 A,8,9,9 A,10 A,10 b,10 c-decahydro-2 A,5 A,6 A,7-tetramethyl-2,5-dioxo-2 H,5 H-cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid methyl ester
Quantity:
5 mg
Molecular Formula:
C27H30O7
CAS:
25990-37-8
Target:
Ubiquitin Ligase (E3) Inhibitors
Purity:
0.97
Chemical Name or Material: 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide
Quantity: 100 mg
Molecular Formula: C8H15N7O2S3
CAS: 76824-35-6
Target: Histamine H2 Receptor Antagonists
Purity: 0.98
Chemical Name or Material:
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide
Quantity:
100 mg
Molecular Formula:
C8H15N7O2S3
CAS:
76824-35-6
Target:
Histamine H2 Receptor Antagonists
Purity:
0.98
Chemical Name or Material: 3-[(2 S)-3-[4-(2-Aminoethyl)-1-piperidinyl]-2-[[(2 ',4 '-dichloro[1,1 '-biphenyl]-3-yl)sulfonyl]amino]-3-oxopropyl]benzenecarboximidamide ditrifluoroacetate
Quantity: 5 mg
Molecular Formula: C29H33Cl2N5O3S0.2 CF3CO2H
CAS: 1268874-09-4
Target: TMPRSS2
Purity: 0.98
Chemical Name or Material:
3-[(2 S)-3-[4-(2-Aminoethyl)-1-piperidinyl]-2-[[(2 ',4 '-dichloro[1,1 '-biphenyl]-3-yl)sulfonyl]amino]-3-oxopropyl]benzenecarboximidamide ditrifluoroacetate
Quantity:
5 mg
Molecular Formula:
C29H33Cl2N5O3S0.2 CF3CO2H
CAS:
1268874-09-4
Target:
TMPRSS2
Purity:
0.98
Chemical Name or Material: (2 S,4 R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-(-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Quantity: 25 mg
Molecular Formula: C30H42FN5O5S0.2 HCl
CAS: 2564467-03-2
Target: Degrader Building Blocks
Purity: 0.95
Chemical Name or Material:
(2 S,4 R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-(-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Quantity:
25 mg
Molecular Formula:
C30H42FN5O5S0.2 HCl
CAS:
2564467-03-2
Target:
Degrader Building Blocks
Purity:
0.95