7237110
Tocris Bioscience™ LW 6
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
Manufacturer: Fischer Scientific
CAS Number: 934593-90-5
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Chemical Name or Material
Methyl 4-hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7 ]dec-1-ylphenoxy)acetyl]amino]benzoate
Target
Dehydrogenase Inhibitors
Purity
0.98
CAS
934593-90-5
Molecular Formula
C26H29NO5
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ LW 6 | Fischer Scientific | ₹ 17,582.58 | |
| | Tocris Bioscience™ LW 6 | Fischer Scientific | ₹ 73,496.04 | |
 | Selleck Chemical LLC LW 6 5mg 934593-90-5 | Selleck Chemical LLC | ₹ 15,092.78 | |
 | Medchemexpress LLC HY-13671 10mg , LW6 CAS:934593-90-5 Purity:>98% | Medchemexpress LLC | ₹ 10,690.72 | |
 | MilliporeSigma™ Calbiochem™ HIF-1 Inhibitor | MilliporeSigma™ | ₹ 21,421.66 | |
 | MilliporeSigma™ Calbiochem™ InSolution™ HIF-1 Inhibitor | MilliporeSigma™ | ₹ 9,668.28 | |
 | 934593-90-5 | LW6 | A2B Chem | ₹ 1,283.40 - ₹ 42,780.00 |
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Description
- LW 6 is a malate dehydrogenase-2 (MDH2) inhibitor (IC50 = 6.3 μM)
- Also inhibits HIF-1α
- Prevents accumulation of HIF-1α in Hep3B cells under hypoxic conditions (IC50 = 2.6 μM) with resulting decrease in expression of HIF-1α target genes VEGF and EPO
- Inhibits proliferation of activated human T cells ex vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: Methyl 4-hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7 ]dec-1-ylphenoxy)acetyl]amino]benzoate
Target: Dehydrogenase Inhibitors
Purity: 0.98
CAS: 934593-90-5
Molecular Formula: C26H29NO5
Chemical Name or Material:
Methyl 4-hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7 ]dec-1-ylphenoxy)acetyl]amino]benzoate
Target:
Dehydrogenase Inhibitors
Purity:
0.98
CAS:
934593-90-5
Molecular Formula:
C26H29NO5
Chemical Name or Material: (2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol
Target: Cyclin-dependent Kinase Inhibitors
Purity: 0.98
CAS: 779353-01-4
Molecular Formula: C21H28N6O2
Chemical Name or Material:
(2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol
Target:
Cyclin-dependent Kinase Inhibitors
Purity:
0.98
CAS:
779353-01-4
Molecular Formula:
C21H28N6O2
Chemical Name or Material: N-[(1 Z)-1-[[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]benzamide
Target: DNA, RNA and Protein Synthesis Inhibitors
Purity: 0.98
CAS: 2141978-86-9
Molecular Formula: C27H25BrN2O3
Chemical Name or Material:
N-[(1 Z)-1-[[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]benzamide
Target:
DNA, RNA and Protein Synthesis Inhibitors
Purity:
0.98
CAS:
2141978-86-9
Molecular Formula:
C27H25BrN2O3
Chemical Name or Material: (2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Target: EGF Receptor Inhibitors
Purity: 0.98
CAS: 698387-09-6
Molecular Formula: C30H29ClN6O3
Chemical Name or Material:
(2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Target:
EGF Receptor Inhibitors
Purity:
0.98
CAS:
698387-09-6
Molecular Formula:
C30H29ClN6O3