7237111
Tocris Bioscience™ Dinaciclib
Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
Manufacturer: Fischer Scientific
CAS Number: 779353-01-4
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Chemical Name or Material
(2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol
Target
Cyclin-dependent Kinase Inhibitors
Purity
0.98
CAS
779353-01-4
Molecular Formula
C21H28N6O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Dinaciclib | Fischer Scientific | ₹ 17,582.58 | |
| | Tocris Bioscience™ Dinaciclib | Fischer Scientific | ₹ 73,496.04 | |
 | Medchemexpress LLC HY-10492 50mg , Dinaciclib CAS:779353-01-4 Purity:>98% | Medchemexpress LLC | ₹ 42,044.18 | |
 | Selleck Chemical LLC Dinaciclib (SCH727965) 10mM/1mL 779353-01-4 PS-095760 | Selleck Chemical LLC | ₹ 27,926.78 | |
 | (2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol | Aaron Chemicals LLC | ₹ 1,540.08 - ₹ 59,293.08 |
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Description
- Dinaciclib is a potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9 activity in vitro (IC50 values are 1, 1, 3 and 4 nM, respectively)
- The compound inhibits DNA replication by blocking thymidine DNA incorporation in A2780 cells (IC50 = 4 nM)
- Dinaciclib induces regression of established solid tumors in mouse models and shows antiviral activity against SARS-CoV-2 in vitro (Vero E6, IC50 = 0.127 μM; A549-ACE2, IC50 = 0.032 μM).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: (2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol
Target: Cyclin-dependent Kinase Inhibitors
Purity: 0.98
CAS: 779353-01-4
Molecular Formula: C21H28N6O2
Chemical Name or Material:
(2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol
Target:
Cyclin-dependent Kinase Inhibitors
Purity:
0.98
CAS:
779353-01-4
Molecular Formula:
C21H28N6O2
Chemical Name or Material: N-[(1 Z)-1-[[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]benzamide
Target: DNA, RNA and Protein Synthesis Inhibitors
Purity: 0.98
CAS: 2141978-86-9
Molecular Formula: C27H25BrN2O3
Chemical Name or Material:
N-[(1 Z)-1-[[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]benzamide
Target:
DNA, RNA and Protein Synthesis Inhibitors
Purity:
0.98
CAS:
2141978-86-9
Molecular Formula:
C27H25BrN2O3
Chemical Name or Material: (2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Target: EGF Receptor Inhibitors
Purity: 0.98
CAS: 698387-09-6
Molecular Formula: C30H29ClN6O3
Chemical Name or Material:
(2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Target:
EGF Receptor Inhibitors
Purity:
0.98
CAS:
698387-09-6
Molecular Formula:
C30H29ClN6O3
Chemical Name or Material: N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Target: Cyclin-dependent Kinase Inhibitors
Purity: 0.98
CAS: 923596-52-5
Molecular Formula: C14H15N5
Chemical Name or Material:
N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Target:
Cyclin-dependent Kinase Inhibitors
Purity:
0.98
CAS:
923596-52-5
Molecular Formula:
C14H15N5