74-071-0

Tocris Bioscience™ LEI 401

Manufacturer: Tocris Bioscience™

CAS Number: 2393840-15-6

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Pack Size SKU Availability Price
Each of 1 74-071-0-Each-of-1 In Stock ₹ 26,566.38

74-071-0 - Each of 1

₹ 26,566.38

In Stock

Quantity

1

Base Price: ₹ 26,566.38

GST (18%): ₹ 4,781.948

Total Price: ₹ 31,348.328

Chemical Name or Material

N-(Cyclopropylmethyl)-6-[(3 S)-3-hydroxy-1-pyrrolidinyl]-2-[(3 S)-3-phenyl-1-piperidinyl]-4-pyrimidinecarboxamide

Quantity

10 mg

Molecular Formula

C24H31N5O2

CAS

2393840-15-6

Target

Phospholipase Inhibitors

Purity

0.98

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Description

  • LEI 401 is a high affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor (Ki = 0.027 and 0.18 μM for human and mouse NAPE-PLD, respectively; IC50 for human enzyme = 0.86 μM)
  • LEI 401 exhibits no significant activity at cannabinoid receptors or other metabolic enzymes of the endocannabinoid system
  • The product reduces levels of N-acylethanolamines (NAE) in a neuroblastoma cell line in vitro
  • It also reduces anandamide levels in mouse brain in vivo and impairs fear extinction
  • LEI 701 is CNS penetrant and cell-permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
N-(Cyclopropylmethyl)-6-[(3 S)-3-hydroxy-1-pyrrolidinyl]-2-[(3 S)-3-phenyl-1-piperidinyl]-4-pyrimidinecarboxamide

Quantity:
10 mg

Molecular Formula:
C24H31N5O2

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2393840-15-6

Target:
Phospholipase Inhibitors

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0.98

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Molecular Formula:
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Chemical Name or Material:
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