74-221-0

Tocris Bioscience™ TH 1760

Manufacturer: Fischer Scientific

CAS Number: 2567914-01-4

Select a Size

Pack Size SKU Availability Price
Each of 1 74-221-0-Each-of-1 In Stock ₹ 17,031.57

74-221-0 - Each of 1

₹ 17,031.57

In Stock

Quantity

1

Base Price: ₹ 17,031.57

GST (18%): ₹ 3,065.683

Total Price: ₹ 20,097.253

Chemical Name or Material

6-[[4-(1 H-Indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3 H)-benzoxazolone

Quantity

10 mg

Molecular Formula

C20H18N4O5S

CAS

2567914-01-4

Target

Hydrolase Inhibitors

Purity

0.95

Other Options

Image Product Name Manufacturer Price Range
200007271
Tocris Bioscience™ TH 1760
Fischer Scientific --
74-225-0
Tocris Bioscience™ TH 1760
Fischer Scientific ₹ 71,296.29

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Potent PARP inhibitor...

Description

  • TH 1760 is a potent and selective NUDT15 (nudix hydrolase 15) inhibitor (IC50 = 29 nM)
  • Displays selectivity for NUDT15 when assayed at 100 μM against other Nudix enzymes (MTH1, NUDT2, 5, 9, 12, 14, 18, 22) and pyrophosphatases or at 10 μM when assayed with a Eurofins Cerep Safety Screen44 panel
  • In vitro , TH 1760 treatment sensitizes cancer cell lines (NB4 and HL-60) to thiopurine.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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Fischer Scientific

74-221-0

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Chemical Name or Material:
6-[[4-(1 H-Indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3 H)-benzoxazolone

Quantity:
10 mg

Molecular Formula:
C20H18N4O5S

CAS:
2567914-01-4

Target:
Hydrolase Inhibitors

Purity:
0.95

Img

Fischer Scientific

74-225-0

--


Chemical Name or Material:
6-[[4-(1 H-Indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3 H)-benzoxazolone

Quantity:
50 mg

Molecular Formula:
C20H18N4O5S

CAS:
2567914-01-4

Target:
Hydrolase Inhibitors

Purity:
0.95

Img

Thermo Scientific™

74-225-Z25KU

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Chemical Name or Material:
__

Quantity:
25 KU

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

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Fischer Scientific

74-231-0

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Chemical Name or Material:
2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide

Quantity:
10 mg

Molecular Formula:
C21H12Cl4N2O3S

CAS:
315224-26-1

Target:
PPAR gamma/NR1C3

Purity:
0.98