75-332

Tocris Bioscience™ ZE 132

Manufacturer: Tocris Bioscience™

CAS Number: 2566710-63-0

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Pack Size SKU Availability Price
Each of 1 75-332-Each-of-1 In Stock ₹ 27,492.14

75-332 - Each of 1

₹ 27,492.14

In Stock

Quantity

1

Base Price: ₹ 27,492.14

GST (18%): ₹ 4,948.585

Total Price: ₹ 32,440.725

Chemical Name or Material

2-[[[5-Chloro-2-[(5-cyano-3-pyridinyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl][3-(dimethylamino)propyl]amino]ethanesulfonic acid

Quantity

2 mg

Molecular Formula

C37H41ClN4O7S

CAS

2566710-63-0

Target

Additional Apoptosis-related Compounds

Purity

0.98

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Description

  • ZE 132 binds to programmed cell death-ligand 1 (PD-L1) with high affinity (KD = 19.36 nM); it potently and selectively inhibits the interaction between programmed cell death-1 (PD-1) and PD-L1 (IC50 = 23.49 nM)
  • ZE 132 promotes CD8+ T cell activation and improves the in vitro cytotoxic killing activity of T-cells
  • ZE 132 treatment can increase Cxcl9 mRNA expression and lower Tgfb1 mRNA expression in CT26 mouse colorectal cancer model
  • ZE 132 shows antitumor effects, inhibiting growth of CT26 tumors in mice by 64%.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
2-[[[5-Chloro-2-[(5-cyano-3-pyridinyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl][3-(dimethylamino)propyl]amino]ethanesulfonic acid

Quantity:
2 mg

Molecular Formula:
C37H41ClN4O7S

CAS:
2566710-63-0

Target:
Additional Apoptosis-related Compounds

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0.98

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10 mg

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C43H75N4O11P.C6H15N

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Fluorescent Lipids Probes and Cell Membrane Stains

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