76-765
Tocris Bioscience™ JQKD 82 dihydrochloride
Manufacturer: Tocris Bioscience™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 76-765-Each-of-1 | In Stock | ₹ 30,349.00 |
76-765 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,349.00
GST (18%): ₹ 5,462.82
Total Price: ₹ 35,811.82
Chemical Name or Material
2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride
Target
Histone Demethylase Inhibitors
Purity
0.98
Quantity
5 mg
Molecular Formula
C27H40N4O50.2 HCl
Related Products
Description
- JQKD 82 dihydrochloride is cell-permeable, selective inhibitor of lysine demethylase 5 (KDM5)
- JQKD 82 does not show activity toward other KDMs; and it has selectivity for KDM5A over other KDM5 isoforms
- JQKD 82 causes hypermethylation of H3K4me3, downregulation of MYC targets and RNAPII phosphorylation; it suppresses multiple myeloma cell (MM.1S) growth (IC50 = 0.42 μmol/L)
- JQKD 82-treated tumors display an increase in H3K4me3 levels and results in a reduction of MYC immuno-staining in NSG mice.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride
Target: Histone Demethylase Inhibitors
Purity: 0.98
Quantity: 5 mg
Molecular Formula: C27H40N4O50.2 HCl
Chemical Name or Material:
2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride
Target:
Histone Demethylase Inhibitors
Purity:
0.98
Quantity:
5 mg
Molecular Formula:
C27H40N4O50.2 HCl
Chemical Name or Material: 3-(5-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Target: Degrader Building Blocks
Purity: __
Quantity: 50 mg
Molecular Formula: C13H13N3O3
Chemical Name or Material:
3-(5-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Target:
Degrader Building Blocks
Purity:
__
Quantity:
50 mg
Molecular Formula:
C13H13N3O3
Chemical Name or Material: 5-Amino-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Target: Degrader Building Blocks
Purity: 0.95
Quantity: 100 mg
Molecular Formula: C13H11N3O4
Chemical Name or Material:
5-Amino-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione
Target:
Degrader Building Blocks
Purity:
0.95
Quantity:
100 mg
Molecular Formula:
C13H11N3O4
Chemical Name or Material: 2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine
Target: DNA, RNA and Protein Synthesis Compounds
Purity: 0.98
Quantity: 10 mg
Molecular Formula: C10H8ClN5O
Chemical Name or Material:
2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine
Target:
DNA, RNA and Protein Synthesis Compounds
Purity:
0.98
Quantity:
10 mg
Molecular Formula:
C10H8ClN5O