77-015
Tocris Bioscience™ RAGE 229
Manufacturer: Tocris Bioscience™
CAS Number: 2143072-85-7
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 77-015-Each-of-1 | In Stock | ₹ 29,603.76 |
77-015 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,603.76
GST (18%): ₹ 5,328.677
Total Price: ₹ 34,932.437
Chemical Name or Material
N-[4-[7-Cyano-4-(4-morpholinylmethyl)-2-quinolinyl]phenyl]acetamide
Quantity
5 mg
Molecular Formula
C23H22N4O2
CAS
2143072-85-7
Target
AGER
Purity
0.98
Related Products
Description
- RAGE 229 is an antagonist of the interaction between the cytoplasmic tail of the receptor for advanced glycation end products (ctRAGE) and the formin, Diaphanous-1 (DIAPH1) (KD for binding to ctRAGE = 2 nM)
- RAGE 229 inhibits the migration of human aortic smooth muscle cells in an in vitro wound healing assay (IC50 = 120 nM)
- RAGE 229 reduces short- and long-term complications of diabetes in mouse models, without lowering blood glucose concentrations
- RAGE 229 also reduces plasma concentrations of TNF-α, IL-6, and CCL2/JE-MCP1 and attenuates inflammatory signaling in diabetic mice.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: N-[4-[7-Cyano-4-(4-morpholinylmethyl)-2-quinolinyl]phenyl]acetamide
Quantity: 5 mg
Molecular Formula: C23H22N4O2
CAS: 2143072-85-7
Target: AGER
Purity: 0.98
Chemical Name or Material:
N-[4-[7-Cyano-4-(4-morpholinylmethyl)-2-quinolinyl]phenyl]acetamide
Quantity:
5 mg
Molecular Formula:
C23H22N4O2
CAS:
2143072-85-7
Target:
AGER
Purity:
0.98
Chemical Name or Material: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Quantity: 10 mg
Molecular Formula: C28H30N6OS
CAS: 790299-79-5
Target: CD117/c-kit
Purity: 0.98
Chemical Name or Material:
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Quantity:
10 mg
Molecular Formula:
C28H30N6OS
CAS:
790299-79-5
Target:
CD117/c-kit
Purity:
0.98
Chemical Name or Material: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Quantity: 50 mg
Molecular Formula: C28H30N6OS
CAS: 790299-79-5
Target: CD117/c-kit
Purity: 0.98
Chemical Name or Material:
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Quantity:
50 mg
Molecular Formula:
C28H30N6OS
CAS:
790299-79-5
Target:
CD117/c-kit
Purity:
0.98
Chemical Name or Material: [P(R)]-5'-O-[(R)-Hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-adenosine cyclic nucleotide disodium
Quantity: 73.5 μg
Molecular Formula: C20H22N10Na2O10P2S2
CAS: 1638750-95-4
Target: STING Agonists
Purity: 95%
Chemical Name or Material:
[P(R)]-5'-O-[(R)-Hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-adenosine cyclic nucleotide disodium
Quantity:
73.5 μg
Molecular Formula:
C20H22N10Na2O10P2S2
CAS:
1638750-95-4
Target:
STING Agonists
Purity:
95%