77-095-0

Tocris Bioscience™ Trametinib

Manufacturer: Fischer Scientific

CAS Number: 871700-17-3

Select a Size

Pack Size SKU Availability Price
Each of 1 77-095-0-Each-of-1 In Stock ₹ 55,314.54

77-095-0 - Each of 1

₹ 55,314.54

In Stock

Quantity

1

Base Price: ₹ 55,314.54

GST (18%): ₹ 9,956.617

Total Price: ₹ 65,271.157

Chemical Name or Material

N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide

Quantity

50 mg

Molecular Formula

C26H23FIN5O4

CAS

871700-17-3

Target

MEK Inhibitors

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250121
Tocris Bioscience™ Trametinib
Fischer Scientific --
77-091-0
Tocris Bioscience™ Trametinib
Fischer Scientific ₹ 13,313.14
NC0596487
Selleck Chemical LLC Trametinib (GSK1120212) 50mg 871700-17-3 JTP-74057, Mekinist
Selleck Chemical LLC ₹ 66,497.23
NC0370092
Selleck Chemical LLC Trametinib (GSK1120212) 5mg 871700-17-3 JTP-74057, Mekinist
Selleck Chemical LLC ₹ 15,092.78
50-201-3673
Enzo Life Sciences Trametinib (100mg). CAS: 871700-17-3
Enzo Life Sciences ₹ 24,696.89
50-201-3676
Enzo Life Sciences Trametinib (1g). CAS: 871700-17-3
Enzo Life Sciences ₹ 1,37,799.51
50-201-3674
Enzo Life Sciences Trametinib (200mg). CAS: 871700-17-3
Enzo Life Sciences ₹ 37,684.90
50-201-3672
Enzo Life Sciences Trametinib (50mg). CAS: 871700-17-3
Enzo Life Sciences ₹ 18,104.50
50-154-280
Biotang Inc Trametinib, > 99%, 200MG, CAS#871700-17-3, M.W.615.39; GSK-1120212, JTP-74057. RS317-200MG
Biotang Inc ₹ 80,193.68
50-201-3670
Enzo Life Sciences Trametinib (10mg). CAS: 871700-17-3
Enzo Life Sciences ₹ 8,166.70

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Description

  • Trametinib is a potent and selective MEK1 and MEK2 inhibitor (IC50 = 0.92 and 1.8 nM, respectively, in cell-free assays)
  • In vitro , it inhibits the growth of human colorectal cancer cell lines expressing either B-RAF or K-RAF (IC50 values range from 0.48 to 36 nM)
  • In vivo , it suppresses tumor growth of HT-29 and COLO205 xenografts in nude mice
  • Trametinib induces apoptosis
  • This compound is orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

77-095-0

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Chemical Name or Material:
N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide

Quantity:
50 mg

Molecular Formula:
C26H23FIN5O4

CAS:
871700-17-3

Target:
MEK Inhibitors

Purity:
0.98

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Chemical Name or Material:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide

Quantity:
10 mg

Molecular Formula:
C19H14Cl2N2O3S

CAS:
879085-55-9

Target:
Hedgehog Signaling Inhibitors

Purity:
0.98

Img

Fischer Scientific

77-105-0

--


Chemical Name or Material:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide

Quantity:
50 mg

Molecular Formula:
C19H14Cl2N2O3S

CAS:
879085-55-9

Target:
Hedgehog Signaling Inhibitors

Purity:
0.98

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Chemical Name or Material:
__

Quantity:
1 mg

Molecular Formula:
__

CAS:
80714-61-0

Target:
__

Purity:
0.95