77-095-0
Tocris Bioscience™ Trametinib
Manufacturer: Fischer Scientific
CAS Number: 871700-17-3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 77-095-0-Each-of-1 | In Stock | ₹ 57,538.50 |
77-095-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,538.50
GST (18%): ₹ 10,356.93
Total Price: ₹ 67,895.43
Chemical Name or Material
N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide
Quantity
50 mg
Molecular Formula
C26H23FIN5O4
CAS
871700-17-3
Target
MEK Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Trametinib | Fischer Scientific | -- | |
| | Tocris Bioscience™ Trametinib | Fischer Scientific | ₹ 13,848.40 | |
 | Selleck Chemical LLC Trametinib (GSK1120212) 50mg 871700-17-3 JTP-74057, Mekinist | Selleck Chemical LLC | ₹ 69,170.80 | |
| | Selleck Chemical LLC Trametinib (GSK1120212) 5mg 871700-17-3 JTP-74057, Mekinist | Selleck Chemical LLC | ₹ 15,699.60 | |
 | Enzo Life Sciences Trametinib (100mg). CAS: 871700-17-3 | Enzo Life Sciences | ₹ 25,689.85 | |
| | Enzo Life Sciences Trametinib (1g). CAS: 871700-17-3 | Enzo Life Sciences | ₹ 1,43,339.84 | |
| | Enzo Life Sciences Trametinib (200mg). CAS: 871700-17-3 | Enzo Life Sciences | ₹ 39,200.05 | |
| | Enzo Life Sciences Trametinib (50mg). CAS: 871700-17-3 | Enzo Life Sciences | ₹ 18,832.40 | |
 | Biotang Inc Trametinib, > 99%, 200MG, CAS#871700-17-3, M.W.615.39; GSK-1120212, JTP-74057. RS317-200MG | Biotang Inc | ₹ 83,417.92 | |
| | Enzo Life Sciences Trametinib (10mg). CAS: 871700-17-3 | Enzo Life Sciences | ₹ 8,495.05 |
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Description
- Trametinib is a potent and selective MEK1 and MEK2 inhibitor (IC50 = 0.92 and 1.8 nM, respectively, in cell-free assays)
- In vitro , it inhibits the growth of human colorectal cancer cell lines expressing either B-RAF or K-RAF (IC50 values range from 0.48 to 36 nM)
- In vivo , it suppresses tumor growth of HT-29 and COLO205 xenografts in nude mice
- Trametinib induces apoptosis
- This compound is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide
Quantity: 50 mg
Molecular Formula: C26H23FIN5O4
CAS: 871700-17-3
Target: MEK Inhibitors
Purity: 0.98
Chemical Name or Material:
N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide
Quantity:
50 mg
Molecular Formula:
C26H23FIN5O4
CAS:
871700-17-3
Target:
MEK Inhibitors
Purity:
0.98
Chemical Name or Material: 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Quantity: 10 mg
Molecular Formula: C19H14Cl2N2O3S
CAS: 879085-55-9
Target: Hedgehog Signaling Inhibitors
Purity: 0.98
Chemical Name or Material:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Quantity:
10 mg
Molecular Formula:
C19H14Cl2N2O3S
CAS:
879085-55-9
Target:
Hedgehog Signaling Inhibitors
Purity:
0.98
Chemical Name or Material: 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Quantity: 50 mg
Molecular Formula: C19H14Cl2N2O3S
CAS: 879085-55-9
Target: Hedgehog Signaling Inhibitors
Purity: 0.98
Chemical Name or Material:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Quantity:
50 mg
Molecular Formula:
C19H14Cl2N2O3S
CAS:
879085-55-9
Target:
Hedgehog Signaling Inhibitors
Purity:
0.98
Chemical Name or Material: __
Quantity: 1 mg
Molecular Formula: __
CAS: 80714-61-0
Target: __
Purity: 0.95
Chemical Name or Material:
__
Quantity:
1 mg
Molecular Formula:
__
CAS:
80714-61-0
Target:
__
Purity:
0.95