77-551-0
Tocris Bioscience™ Asunaprevir
Manufacturer: Fischer Scientific
CAS Number: 630420-16-5
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 77-551-0-Each-of-1 | In Stock | ₹ 26,095.80 |
77-551-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,095.80
GST (18%): ₹ 4,697.244
Total Price: ₹ 30,793.044
Chemical Name or Material
1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Quantity
10 mg
Molecular Formula
C35H46ClN5O9S
CAS
630420-16-5
Target
CRISPR Reagents
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Asunaprevir | Fischer Scientific | -- | |
| | Tocris Bioscience™ Asunaprevir | Fischer Scientific | ₹ 1,09,345.68 | |
 | Medchemexpress LLC Asunaprevir | 630420-16-5 | MFCD27987900 | 10 mm/mL | Medchemexpress LLC | ₹ 20,213.55 | |
 | eMolecules AstaTech / ASUNAPREVIR / 0.01g / 449732111 / 43208 / 95.000 / 630420-16-5 / MFCD27987900 / 748.290 / C35H46ClN5O9S | eMolecules | ₹ 8,690.33 | |
 | Apexbio Technology LLC Asunaprevir (BMS-650032), 10mg. Cas: 630420-16-5 MFCD: MFCD27987900. NS3 protease inhibitor | Apexbio Technology LLC | ₹ 32,512.80 | |
 | (1R,2S)-N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenylcyclopropanecarboxamide | Aaron Chemicals LLC | ₹ 2,737.92 - ₹ 1,30,393.44 |
Related Products
Description
- Asunaprevir is a potent HCV NS3 protease inhibitor (IC50 = 0.2-3.5 nM)
- Asunaprevir can be used to control CRIPSR-Cas9 gene editing via the small molecule-assisted shut-off (SMASh) technique, which involves fusion of Cas9 to a peptide comprising a protease domain and a degron tag
- Asuprenavir blocks the protease-mediated removal of the degron tag leading to degradation of Cas9 through proteasome and autophagolysosome pathways
- It can also be used as a resversible switch to control CAR (chimeric antigen receptor)-T cells, where the CAR has been modified by insertion of a hepatitis C virus nonstructural protein 3 protease (HCV-NS3) between the scFv and the hinge domains
- Also inhibits SARS-CoV-2 Mpro activity (IC50 = 15-48.4 μM).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Quantity: 10 mg
Molecular Formula: C35H46ClN5O9S
CAS: 630420-16-5
Target: CRISPR Reagents
Purity: 0.98
Chemical Name or Material:
1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Quantity:
10 mg
Molecular Formula:
C35H46ClN5O9S
CAS:
630420-16-5
Target:
CRISPR Reagents
Purity:
0.98
Chemical Name or Material: 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Quantity: 50 mg
Molecular Formula: C35H46ClN5O9S
CAS: 630420-16-5
Target: CRISPR Reagents
Purity: 0.98
Chemical Name or Material:
1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1 R,2 S)-2-vinylcyclopropane-1-carboxamide
Quantity:
50 mg
Molecular Formula:
C35H46ClN5O9S
CAS:
630420-16-5
Target:
CRISPR Reagents
Purity:
0.98
Chemical Name or Material: (1R,2R,5S)-11-(8-((1-(2-Fluoro-2-methylpropyl)piperidin-4-yl)amino)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl)-2-isopropyl-2,3,5,6-tetrahydro-1,5-epiminobenzo[d]azocin-4(1H)-one
Quantity: 2 mg
Molecular Formula: C30H39FN8O2
CAS: __
Target: ATAD2
Purity: __
Chemical Name or Material:
(1R,2R,5S)-11-(8-((1-(2-Fluoro-2-methylpropyl)piperidin-4-yl)amino)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine-6-carbonyl)-2-isopropyl-2,3,5,6-tetrahydro-1,5-epiminobenzo[d]azocin-4(1H)-one
Quantity:
2 mg
Molecular Formula:
C30H39FN8O2
CAS:
__
Target:
ATAD2
Purity:
__
Chemical Name or Material: -3-[[[(2 S,4 R)-1-[-2-(1-Fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxypyrrolidin-2-yl]carbonyl]amino]-3-[4-(4-methylthiazol-5-yl)phenyl]propanoic acid
Quantity: 50 mg
Molecular Formula: C28H35FN4O6S
CAS: 2408341-97-7
Target: Degrader Building Blocks
Purity: 0.98
Chemical Name or Material:
-3-[[[(2 S,4 R)-1-[-2-(1-Fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxypyrrolidin-2-yl]carbonyl]amino]-3-[4-(4-methylthiazol-5-yl)phenyl]propanoic acid
Quantity:
50 mg
Molecular Formula:
C28H35FN4O6S
CAS:
2408341-97-7
Target:
Degrader Building Blocks
Purity:
0.98